37517-79-6

Upstream product

• 72957-88-1 6-exo-(3'-t-butyldimethylsilyloxyoct-1'-enyl)-2-oxabicyclo<3.3.0>oct-7-en-3-one 
• 72971-56-3 11-deoxa-10,11-dehydro-15-t-butyldimethylsilyloxyprostaglandin F_1α 
• 75758-61-1 15-t-butyldimethylsilyloxyprostaglandin A₂ 
• 81424-08-0 11-deoxy-PGE₂-15-tert-butyldimethylsilyl ether 
• 75758-61-1 (Z)-7-{(1S,2R)-2-[(E)-(R)-3-(tert-Butyl-dimethyl-silanyloxy)-oct-1-enyl]-5-oxo-cyclopent-3-enyl}-hept-5-enoic acid 
• 17814-85-6 (4-carboxybutyl)triphenylphosphonium bromide 
• 81424-09-1 C₃₂H₆₂O₄Si₃ 
• 72957-90-5 6-exo-(3'-t-butyldimethylsilyloxyoct-1'-enyl)-2-oxabicyclo<3.3.0>oct-7-en-3-ol 

Relevant academic research and scientific papers

First total synthesis of A2 isoprostane

A stereoselective Julia-Lythgoe olefination has allowed the first total synthesis of A2 isoprostane (1), a recently discovered member of the growing isoprostane family. This elusive compound opens up numerous new avenues for the molecular biology of cyclopentenone prostaglandins, which are endowed of intriguing biological effects such as antitumor, antiinflammatory, and antiviral activities.

The Total Synthesis of Prostaglandins by the Tropolone Route

A general synthesis from α-tropolone methyl ether of natural and modified prostaglandins is detailed.A key intermediate in the synthesis, 7-methoxybicyclohepta-3,6-dien-2-one, has been secured from α-tropolone methyl ether in improved yield and con

Total Synthesis of Prostaglandin A2 involving the Reaction of a Heterocuprate Reagent with an Allyl Epoxide

A new route to prostaglandin A2 (18) involves as the key step the SN' anti reaction of the allyl epoxide (12) and the cuprate reagent (9).