375348-49-5
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Basic information
- Product Name: Bertilimumab
- Synonyms: Bertilimumab;Bertilimumab [inn];Cat-213;Human anti-eotaxin 1 monoclonal antibody;Immunoglobulin G4, anti-(human eotaxin 1) (human monoclonal cat-213 gamma 4-chain), disulfide with human monoclonal cat-213 kappachain, dimer
- CAS NO:375348-49-5
- Molecular Formula:
- Molecular Weight: 0
- EINECS: N/A
- Product Categories: N/A
- Mol File: 375348-49-5.mol
- Article Data: 0
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: Bertilimumab(CAS DataBase Reference)
- NIST Chemistry Reference: Bertilimumab(375348-49-5)
- EPA Substance Registry System: Bertilimumab(375348-49-5)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 375348-49-5(Hazardous Substances Data)
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375348-49-5 Usage
General Description
Bertilimumab is a monoclonal antibody that targets and inhibits the activity of eotaxin-1, a chemokine involved in recruiting eosinophils to sites of inflammation. Eosinophils are white blood cells that play a role in allergic and autoimmune responses, and their over-activation can lead to tissue damage and inflammation. By blocking the action of eotaxin-1, bertilimumab is designed to reduce the infiltration of eosinophils into inflamed tissues, thereby mitigating the associated inflammatory response. This makes bertilimumab a potential treatment for conditions such as asthma, atopic dermatitis, and inflammatory bowel disease, where eosinophil-mediated inflammation is a key factor in disease pathology.Check Digit Verification of cas no
The CAS Registry Mumber 375348-49-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,7,5,3,4 and 8 respectively; the second part has 2 digits, 4 and 9 respectively.Calculate Digit Verification of CAS Registry Number 375348-49:
(8*3)+(7*7)+(6*5)+(5*3)+(4*4)+(3*8)+(2*4)+(1*9)=175
175 % 10 = 5
So 375348-49-5 is a valid CAS Registry Number.
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Bertilimumab
