37535-57-2

Basic information

• Product Name: (S)-N-Boc-(4-Pyridyl)alanine
• Synonyms: BOC-(S)-2-AMINO-3-(4'-PYRIDYL)PROPANOIC ACID;BOC-BETA-(4-PYRIDYL)-L-ALANINE;BOC-ALA(4'-PYRIDYL)-OH;BOC-ALA(4-PYRIDYL)-OH;BOC-ALA(4-PYRI)-OH;BOC-4'-PYRIDYL-L-ALA;BOC-4-PAL-OH;BOC-3-(4'-PYRIDYL)-L-ALANINE
• CAS NO: 37535-57-2
• Molecular Formula: C₁₃H₁₈N₂O₄
• Molecular Weight: 266.29
• Product Categories: Amino Acids;Phenylalanine analogs and other aromatic alpha amino acids;Amino Acid Derivatives;Unusual Amino Acids;a-amino
• Mol File: 37535-57-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 409.5°C (rough estimate)
• Flash Point: 228.5 °C
• Appearance: off-white to light yellow powder
• Density: 1.1738 (rough estimate)
• Vapor Pressure: 4.82E-09mmHg at 25°C
• Refractive Index: 1.6450 (estimate)
• Storage Temp.: 2-8°C
• PKA: 3.43±0.10(Predicted)
• Sensitive: Air & Moisture Sensitive
• BRN: 6417084
• CAS DataBase Reference: (S)-N-Boc-(4-Pyridyl)alanine(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-N-Boc-(4-Pyridyl)alanine(37535-57-2)
• EPA Substance Registry System: (S)-N-Boc-(4-Pyridyl)alanine(37535-57-2)

Safety Data

• Hazard Codes: Xi
• WGK Germany: 3
• F: 1-10
• HazardClass: IRRITANT
• Hazardous Substances Data: 37535-57-2(Hazardous Substances Data)

Usage

Chemical Properties

off-white to light yellow powder

Uses

Boc-3-(4-pyridyl)-L-alanine is the protected form of L-Alanine (A481500), a non-essential amino acid that can be found naturally in the human body and is obtained by our diet.

InChI:InChI=1/C13H18N2O4/c1-13(2,3)19-12(18)15-10(11(16)17)8-9-4-6-14-7-5-9/h4-7,10H,8H2,1-3H3,(H,15,18)(H,16,17)/t10-/m0/s1

Upstream product

• 178933-04-5 L-3-(4-pyridyl)alanine dihydrochloride 
• 24424-99-5 di-tert-butyl dicarbonate 
• 37535-49-2 (S)-2-amino-3-(pyridin-4-yl)propanoic acid 

Downstream Products

• 1416468-94-4 (4aS,8aR)-2-{1-[(2S)-2-amino-3-(pyridin-4-yl)propanoyl]piperidin-4-yl}-4-(3,4-dimethoxyphenyl)-4a,5,6,7,8,8a-hexahydrophthalazin-1(2H)-one hydrochloride 
• 1416468-95-5 tert-butyl [(2S)-1-{4-[(4aS,8aR)-4-(3,4-dimethoxyphenyl)-1-oxo-4a,5,6,7,8,8a-hexahydrophthalazin-2(1H)-yl]piperidin-1-yl}-1-oxo-3-(pyridin-4-yl)propan-2-yl]carbamate 
• 1534361-70-0 1,1,1,3,3,3-hexafluoro-2-(4-(2-(4-pyridinylmethyl)-4-(2-thiophenylsulfonyl)-1-piperazinyl)phenyl)-2-propanol 
• 907972-04-7 2-(pyridin-4-yl-methyl)piperazine 
• 1421639-80-6 C₃₁H₄₃N₇O₅S 
• 1421639-75-9 C₃₅H₄₄N₈O₅S 
• 1421640-03-0 N₃-Phe-Ala(4-pyridine)-Leu-NHNH₂ 
• 1421640-02-9 N₃-Phe-Ala(4-pyridine)-Leu-OMe 
• 1416467-45-2 4-[5-(cyclopropylmethoxy)-1,3-benzodioxol-4-yl]-N-[(2S)-1-{4-[(4aS,8aR)-4-(3,4-dimethoxyphenyl)-1-oxo-4a,5,6,7,8,8a-hexahydrophthalazin-2(1H)-yl]piperidin-1-yl}-1-oxo-3-(pyridin-4-yl)propan-2-yl]-5H-pyrrolo[3,2-d]pyrimidine-7-carboxamide 

Relevant articles and documents

EPOXYKETONE COMPOUNDS FOR ENZYME INHIBITION

The present disclosure relates to novel compounds and pharmaceutical compositions thereof which are useful as inhibitors of proteasomes. The compounds provided herein have improved proteasome potency and selectivity, and increased aqueous solubility, and

Studies on polypeptides XXXII. Solid-phase synthesis of RNase S-peptide 1-14 analogues; replacement of histidine-12 by β-(2-pyridyl)-L-alanine and β-(4-pyridyl)-L-alanine

The synthesis of two analogues of the N-terminal tetradecapeptide of ribonuclease A (RNase S-peptide 1-14), in which the active site histidine-12 residue is replaced by β-(2-pyridyl)-L-alanine and β-(4-pyridyl)-L-alanine, has been accomplished by the solid-phase method.The enantiomers of β-(2-pyridyl)alanine were obtained by chymotryptic hydrolysis of its racemic Nα-acetyl ethyl ester.The Boc derivative of both L-amino acids has been synthesized.