375357-76-9

Basic information

• Product Name: (E)-4-((3-(ethoxycarbonyl)-6-methyl-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)amino)-4-oxobut-2-enoic acid
• Synonyms: (E)-4-((3-(ethoxycarbonyl)-6-methyl-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)amino)-4-oxobut-2-enoic acid;(2Z)-4-{[3-(ethoxycarbonyl)-6-methyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl]amino}-4-oxobut-2-enoic acid;4-{[3-(ethoxycarbonyl)-6-methyl-4,5,6,7-tetrahydro-1-benzothien-2-yl]amino}-4-oxo-2-butenoic acid
• CAS NO: 375357-76-9
• Molecular Formula: C16H19NO5S
• Molecular Weight: 337.39076
• Mol File: 375357-76-9.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (E)-4-((3-(ethoxycarbonyl)-6-methyl-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)amino)-4-oxobut-2-enoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-4-((3-(ethoxycarbonyl)-6-methyl-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)amino)-4-oxobut-2-enoic acid(375357-76-9)
• EPA Substance Registry System: (E)-4-((3-(ethoxycarbonyl)-6-methyl-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)amino)-4-oxobut-2-enoic acid(375357-76-9)

Safety Data

• Hazardous Substances Data: 375357-76-9(Hazardous Substances Data)

Upstream product

• 589-92-4 1-methylcyclohexan-4-one 
• 108-31-6 maleic anhydride 
• 76981-71-0 2-amino-6-methyl-4,5,6,7-tetrahydro-benzo[b]thiophene-3-carboxylic acid ethyl ester 
• 105-56-6 ethyl 2-cyanoacetate 

Relevant articles and documents

An NMDAR positive and negative allosteric modulator series share a binding site and are interconverted by methyl groups

N-methyl-D-aspartate receptors (NMDARs) are an important receptor in the brain and have been implicated in multiple neurological disorders. Many non-selective NMDAR-targeting drugs are poorly tolerated, leading to efforts to target NMDAR subtyp