375368-78-8 Usage
Description
3-Bromo-2-fluoro-6-picoline, a halogenated derivative of picoline with the molecular formula C6H4BrFN, is a substituted pyridine compound. It is characterized by its pale yellow color, pungent odor, and high flammability. Due to its potent irritant properties to the skin, eyes, and respiratory system, it requires careful handling in a well-ventilated environment with appropriate personal protective equipment.
Uses
Used in Pharmaceutical Industry:
3-Bromo-2-fluoro-6-picoline is used as a key intermediate in the synthesis of various pharmaceuticals. Its unique halogenated structure allows for the development of new drugs with improved therapeutic properties and efficacy.
Used in Agrochemical Industry:
In the agrochemical sector, 3-Bromo-2-fluoro-6-picoline serves as an essential building block for the production of various agrochemicals. Its incorporation into these compounds can enhance their pesticidal or herbicidal activities, contributing to more effective crop protection.
Used in Organic Synthesis:
3-Bromo-2-fluoro-6-picoline is utilized as a versatile intermediate in the synthesis of a wide range of organic compounds. Its reactivity and functional group compatibility make it a valuable component in the creation of novel molecules for various applications, including materials science and specialty chemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 375368-78-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,7,5,3,6 and 8 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 375368-78:
(8*3)+(7*7)+(6*5)+(5*3)+(4*6)+(3*8)+(2*7)+(1*8)=188
188 % 10 = 8
So 375368-78-8 is a valid CAS Registry Number.
InChI:InChI=1/C6H5BrFN/c1-4-2-3-5(7)6(8)9-4/h2-3H,1H3
375368-78-8Relevant articles and documents
Preparation method of poly-substitution 6-fluorine picolinic acid
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Paragraph 0025; 0027; 0031; 0032, (2018/09/08)
The invention discloses a preparation method of poly-substitution 6-fluorine picolinic acid. The preparation method comprises the following steps: performing diazotization on the poly-substitution 2-amino-6-picoline and a diazotized agent; performing a reaction on a fluorinating agent to generate the poly-substitution 2-amino-6-fluoride pyridine; performing an oxidizing reaction on the poly-substitution 6-picoline-2-fluoride pyridine and an oxidizing agent to obtain the poly-substitution 6-fluorine picolinic acid. The invention provides a novel initial raw material for preparing poly-substitution 6-fluorine picolinic acid, and correspondingly provides a novel reaction path and process. The poly-substitution 2-amino-6-picoline is taken as the initial raw material has the advantages of low cost and readily-available; the prepared 6-fluorine picolinic acid has the advantages of simple process, low requirement on reaction conditions, high security performance, high product yield and purityand easiness in realizing scale production.
