3754-19-6 Usage
Uses
Used in Pharmaceutical Industry:
Ambuside is used as a diuretic agent for its ability to increase the rate of urine flow and help remove excess water and salts from the body, which can be beneficial in treating conditions like edema and high blood pressure.
Used in Biomedical Research:
In the field of biological studies, ambuside is utilized in the discovery of novel trypanosomicidal drug-like chemicals. These studies aim to identify new compounds that can effectively combat trypanosomiasis, a disease caused by the parasitic protozoa of the genus Trypanosoma.
Originator
Hydrion,Robert and
Carriere,France,1970
Manufacturing Process
Preparation of 2-Allylsulfamyl-4-Sulfamyl-5-Chloro-N-(3-Hydroxy-2-
Butenylidene)Aniline or Ambuside: 2-allylsulfamyl-5-chloro-4-
sulfamylanilinemonohydrate (6.9 grams, 0.020 mol) was dissolved in 14 ml
acetylacetaldehyde dimethylacetal at room temperature and the viscous
solution was filtered. Addition of 6 drops of 10:1 H2O/concentrated HCl, and
stirring for 20 hours gave a heavy suspension. Dilution with 150 ml of
ethanol, collection of the solid, washing twice with 40 ml portions of ethanol,
and drying gave 6.2 grams (78%) of product, MP 204-206°C.
Therapeutic Function
Diuretic, Antihypertensive
Check Digit Verification of cas no
The CAS Registry Mumber 3754-19-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,7,5 and 4 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 3754-19:
(6*3)+(5*7)+(4*5)+(3*4)+(2*1)+(1*9)=96
96 % 10 = 6
So 3754-19-6 is a valid CAS Registry Number.
InChI:InChI=1/C13H16ClN3O5S2/c1-3-5-17-24(21,22)13-8-12(23(15,19)20)10(14)7-11(13)16-6-4-9(2)18/h3-4,6-8,17-18H,1,5H2,2H3,(H2,15,19,20)/b9-4-,16-6+
