37551-43-2

Basic information

• Product Name: 5-CHLORO-N,2-DIHYDROXYBENZAMIDE
• Synonyms: 5-CHLORO-N,2-DIHYDROXYBENZAMIDE;5-CHLORO-2-HYDROXYBENZOHYDROXAMIC ACID;5-Chloro-N,2-dihydrobenzamide
• CAS NO: 37551-43-2
• Molecular Formula: C₇H₆ClNO₃
• Molecular Weight: 187.58
• EINECS: 253-550-0
• Product Categories: Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
• Mol File: 37551-43-2.mol
• Article Data: 5

Chemical Properties

• Melting Point: 208℃
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.548g/cm³
• Refractive Index: 1.638
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 5-CHLORO-N,2-DIHYDROXYBENZAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-CHLORO-N,2-DIHYDROXYBENZAMIDE(37551-43-2)
• EPA Substance Registry System: 5-CHLORO-N,2-DIHYDROXYBENZAMIDE(37551-43-2)

Safety Data

• Hazard Codes: Xi:Irritant
• Statements: R36/37/38:Irritating to eyes, respiratory system and skin.
• Safety Statements: S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.; S37/39:Wear suitable g
• Hazardous Substances Data: 37551-43-2(Hazardous Substances Data)

Usage

General Description

5-Chloro-N,2-dihydroxybenzamide, also known as 5CQA, is a chlorinated derivative of quinic acid, and is most commonly found in various types of roasted coffee. As a hydroxybenzamide compound, it has potential antioxidant and anticancer properties. The chlorination process of this specific chemical affects both the taste of coffee and its potential health benefits. It is categorized as an acid, and it is typically found in a solid state. However, detailed properties, including its molecular formula, molar mass, melting or boiling points, and other safety or hazard information, are not widely available, indicating that further comprehensive research is necessary.

InChI:InChI=1/C7H6ClNO3/c8-4-1-2-6(10)5(3-4)7(11)9-12/h1-3,10,12H,(H,9,11)

Upstream product

• 4068-78-4 methyl 5-chloro-2-hydroxybenzoate 
• 321-14-2 5-chloro-2-hydroxybenzoic acid 

Downstream Products

• 24603-63-2 5-chloro-3-hydroxy-1,2-benzoisoxazole 
• 24603-63-2 5-Chloro-benzo[d]isoxazol-3-one 
• 29053-27-8 7-chloro-2c-methyl-(3ar)-3,3a-dihydro-2H-benzo[e]isoxazolo[3,2-b][1,3]oxazin-9-one 
• 29053-27-8 7-chloro-2t-methyl-(3ar)-3,3a-dihydro-2H-benzo[e]isoxazolo[3,2-b][1,3]oxazin-9-one 
• 29050-11-1 7-chloro-3,3a-dihydro-2H-benzo[e]isoxazolo[3,2-b][1,3]oxazin-9-one 
• 16263-53-9 3,5-dichloro-1,2-benzoisoxazole 
• 63482-60-0 6-chloro-2-(2-chloro-propyl)-3-hydroxy-2,3-dihydro-benzo[e][1,3]oxazin-4-one 
• 29050-04-2 6-chloro-2-(2-chloro-ethyl)-3-hydroxy-2,3-dihydro-benzo[e][1,3]oxazin-4-one 
• 95-25-0 5-chloro-2-benzoxazolinone 

Relevant articles and documents

Family of mixed 3d-4f dimeric 14-metallacrown-5 compounds: Syntheses, structures, and magnetic properties

An isomorphous family of mixed 3d-4f dodenuclear aggregates, {[Mn III8Ln4(Clshi)8(OAc) 6(μ3-OCH3)2(μ3-O) 2(CH3OH)12(H2O)2] ·4CH3OH·xH2O)} (where Ln = EuIII (1), GdIII (2), TbIII (3), and DyIII (4); ClshiH3 = 5-chlorosalicylhydroxamic acid; x = 5 for 1 and 3; x = 6 for 2; x = 2 for 4), were synthesized and characterized. They were obtained from the reaction of ClshiH3 with Mn(OAc)2·4H 2O and Ln(NO3)3·6H2O. These isomorphous mixed 3d-4f compounds represent a family of novel structures with lanthanide ions in the metallacrown (MC) ring. Each dodecanuclear aggregate contains two offset stacked 14-MC-5 units with M-N-O-M-N-O-Ln-O-N-M-O-N-M connectivity to capture one LnIII ion in the core of each MC. Two 14-MC-5 units are connected through O ions with four Mn ions and six O atoms arranged in a double Mn4O6 cubane. Magnetic measurement indicates that antiferromagnetic interactions are present between the metal ions. The DyIII analogue with high anisotropy and large spin shows slow magnetization relaxation at a direct-current field of 2 kOe.

Method for lowering serum uric acid

A method for lowering serum uric acid is disclosed which comprises administering to a human for its uricosuric activity a pharmaceutical composition comprising 7-chloro-2-methyl-3,3a-dihydro-2H,9H-isoxazolo (3,2-b) (1,3)-benzoxazin-9-one. 7-chloro-2-methyl-3,3a-dihydro-2H,9H-isoxazolo (3,2-b) (1,3) benzoxazin-9-one is a useful compound having valuable pharmacological properties, for example, it is a valuable anti-inflammatory agent, as evidenced by its ability to inhibit the local edema formation characteristic of inflammatory states when administered systemically to warm-blooded animals.

The tuberculostatic hydroxamic acids.

-