37574-47-3

Usage

Safety Profile

Questionable carcinogen withexperimental tumorigenic and neoplastigenic data.Mutation data reported. When heated to decomposition itemits acrid and irritating fumes.

InChI:InChI=1/C20H12O/c1-2-6-13-12(4-1)10-16-18-14(13)9-8-11-5-3-7-15(17(11)18)19-20(16)21-19/h1-10,19-20H

Upstream product

• 78031-10-4 ((1R,2S,5R)-2-Isopropyl-5-methyl-cyclohexyloxy)-acetic acid (4R,5R)-4-[2-((1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyloxy)-acetoxy]-4,5-dihydro-benzo[def]chrysen-5-yl ester 
• 62600-10-6 4(R),5(R)-4,5-dihydrobenzopyrene-4,5-diol 
• 50-32-8 benzopyrene 

Downstream Products

• 37574-48-4 4-hydroxybenzoanthracene 
• 56182-99-1 4-methoxybenzoanthracene 
• 56183-00-7 5-methoxybenzoanthracene 
• 28622-84-6 4,5-dihydrobenzopyrene-4,5-trans-(e,e)-diol 
• 24027-84-7 5-hydroxy-benzo[a]pyrene 
• 50-32-8 benzopyrene 
• 110418-68-3 (+/-)-trans-4-methoxy-5-hydroxy-4,5-dihydrobenzopyrene 
• 110418-69-4 (+/-)-trans-4-hydroxy-5-methoxy-4,5-dihydrobenzopyrene 

Relevant academic research and scientific papers

DIRECT EPOXIDATION OF POLYCYCLIC AROMATIC COMPOUNDS BY SUPEROXIDE IN THE PRESENCE OF PHOSGENE DIMER

Olefins and polycyclic aromatic compounds were oxidized to their epoxides by superoxide (O2-.) in the presence of phosgene dimer.The reaction mechanisms are discussed.

ABSOLUTE CONFIGURATION OF THE K-REGION 4,5-DIHYDRODIOLS AND 4,5-OXIDE OF BENZOPYRENE

Application of the exciton chirality rule has allowed assignment of absolute configuration to (+)-trans-(4R,5R)-dihydroxy-4,5-dihydrobenzopyrene, a mammalian metabolite of the hydrocarbon.The cis 4,5-dihydrodiol and 4,5-oxide are also assigned based on correlation with the trans dihydrodiol.