375792-70-4Relevant academic research and scientific papers
A new bicyclic dipeptide isostere with pyrrolizidinone skeleton
Cordero, Franca M.,Pisaneschi, Federica,Batista, Karina Meschini,Valenza, Silvia,Machetti, Fabrizio,Brandi, Alberto
, p. 856 - 867 (2007/10/03)
(Chemical Equation Presented) The synthesis of a new conformationally constrained Gly-(s-cis)Pro Turn Mimetic (GPTM) in both racemic and enantiomerically pure forms and their incorporation into peptides 18, 21, and 24 are reported. The synthetic strategy
Bicyclic dipeptide isosteres, their preparation and use as beta-turn mimics
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, (2008/06/13)
The present invention relates to bicyclic dipeptide isosteres of general formula (I) their preparation by a cycloaddition/cyclization process and their use as Beta-turn Mimics.
Design and synthesis of a new bicyclic dipeptide isostere
Cordero,Valenza,Machetti,Brandi
, p. 1590 - 1591 (2007/10/03)
The synthesis of a new Gly-Pro turn mimetic and the computational study of its ability to induce β-turn is reported.
