37581-44-5 Usage
Uses
Used in Pharmaceutical Industry:
2,6-Diethylisonicotinonitrile is used as a key intermediate compound for the synthesis of P3' ligands. These ligands are crucial in the preparation of hydroxyethylpiperazine derivatives, which act as HIV-1 protease inhibitors. 2,6-Diethylisonicotinonitrile plays a significant role in the development of antiretroviral drugs, contributing to the fight against HIV and AIDS.
The application of 2,6-Diethylisonicotinonitrile in the pharmaceutical industry is primarily due to its ability to form P3' ligands, which are essential components in the synthesis of hydroxyethylpiperazine derivatives. These derivatives have been found to be effective HIV-1 protease inhibitors, making them valuable in the development of antiretroviral medications. By incorporating 2,6-Diethylisonicotinonitrile into the synthesis process, researchers can create more potent and targeted treatments for HIV and AIDS, ultimately improving the quality of life for those affected by these diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 37581-44-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,7,5,8 and 1 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 37581-44:
(7*3)+(6*7)+(5*5)+(4*8)+(3*1)+(2*4)+(1*4)=135
135 % 10 = 5
So 37581-44-5 is a valid CAS Registry Number.
37581-44-5Relevant academic research and scientific papers
COMPOUNDS AND THEIR USE AS PDE4 ACTIVATORS
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Page/Page column 85-86, (2019/10/29)
The present invention relates to compounds as defined herein, which are activators of long form cyclic nucleotide phosphodiesterase-4 (PDE4) enzymes (isoforms) and to therapies using these activators. In particular, the invention relates to these activator compounds for use in a method for the treatment or prevention of disorders requiring a reduction of second messenger responses mediated by cyclic 3',5-adenosine monophosphate (cAMP).
