37586-96-2

Upstream product

• 1076-38-6 4-hydroxy[1]benzopyran-2-one 
• 23718-99-2 2-methylene-1,3-diphenylpropane-1,3-dione 
• 85054-03-1 2-Methanesulfinylmethyl-1,3-diphenyl-propane-1,3-dione 

Downstream Products

• 88404-98-2 (2S,3R)-3-Benzoyl-2-methoxy-2-phenyl-3,4-dihydro-2H-pyrano[3,2-c]chromen-5-one 
• 88404-98-2 (2S,3S)-3-Benzoyl-2-methoxy-2-phenyl-3,4-dihydro-2H-pyrano[3,2-c]chromen-5-one 

Relevant academic research and scientific papers

Reactivity of 2-Methylene-1,3-dicarbonyl Compounds. Syntheses of 2,2,3-Trisubstituted-3,4-dihydro-2H-pyranobenzopyran-5-ones

Michael condensation of 2-methylsulfinylmethyl-1,3-dicarbonyl compounds (3) or 2-methylene-1,3-dicarbonyl compounds (4) with 4-hydroxycoumarin (5) at ambient temperature gave 2--1,3-dicarbonyl compounds (6).Treatment of 6 with methanolic hydrogen chloride resulted in the regioselective formation of 2,2,3-trisubstituted-3,4-dihydro-2H-pyranobenzopyran-5-ones.Keywords - 2-methylene-1,3-dicarbonyl compound; 2-methylsulfinylmethyl-1,3-dicarbonyl compound; 2,2,3-trisubstituted-3,4-dihydro-2H-pyranobenzopyran-5-one; regioselective cyclization; Michael condensation