37591-56-3

Upstream product

• 66363-41-5 (S)-3,3-Dimethyl-7-oxo-6-phenylacetylamino-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid benzhydryl ester 
• 101760-76-3 (2S,4R,5R,6R)-6-(Bis-phenylacetyl-amino)-3,3-dimethyl-4,7-dioxo-4λ⁴-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid benzhydryl ester 
• 114-70-5 sodium phenylacetate 
• 101760-73-0 (2S,5R,6R)-6-(Bis-phenylacetyl-amino)-3,3-dimethyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid benzhydryl ester 
• 67565-52-0 diphenylmethyl 6β-(2-phenylacetamido)penicillanate 

Downstream Products

• 78037-13-5 (R)-2-((1S,5R)-3-Benzyl-7-oxo-4-oxa-2,6-diaza-bicyclo[3.2.0]hept-2-en-6-yl)-3-methyl-but-3-enoic acid benzhydryl ester 
• 51415-50-0 10-chloro-6β-(2-phenyl-acetylamino)-penicillanic acid benzhydryl ester 
• 100298-43-9 benzhydryl 6-diazopenicillanate 1β-oxide 
• 100349-42-6 (2S,4S,5R)-3,3-dimethyl-4,7-dioxo-4-thia-1-azabicyclo<3.2.0>heptane-2-carboxylic acid benzhydryl ester 
• 100349-41-5 (2S,4S,5R,6S)-6-bromo-3,3-dimethyl-4,7-dioxo-4-thia-1-azabicyclo<3.2.0>heptane-2-carboxylic acid benzhydryl ester 

Relevant academic research and scientific papers

Oxidation Studies on β-Lactam Antibiotics. The 6-(Diacylamino)penicillins

The oxidation of the 6-(diacylamino)penicillins is a convenient, high yield route to the penicillin 1α-sulfoxides.The yield of the 1α-sulfoxide is dependent on the solvent, the temperature, the C-3 ester function, and the substituent at the C-2 position.T

Process for the preparation of esters of N-blocked penicillin acids which comprises reacting the acid or a salt thereof with a primary amine and a nitrosating agent

A process is described for the preparation of esters of N-blocked amino acids (such as penicillins or cephalosporins) wherein the amino acid or a salt thereof is reacted with a primary amine and nitrosating agent.