37613-74-4Relevant academic research and scientific papers
Cyclopentenyl ethylamines active on CNS
Mule,Pirisino,Moretti,Sparatore,Manca Dimich,Satta,Peana
, p. 1161 - 1172 (2007/10/02)
Two new cyclopentenylethylamines were prepared and were submitted to a pharmacological screening together with some others previously described and now reprepared. All compounds exhibited different degrees of depressive activity on CNS and good analgesic activity. Compound 5, bearing a phenyl group on the carbon atom to which the amino group is connected, appears rather interesting being the most active as analgesic and the least toxic. Compounds 2 and 3 are able to antagonize in a certain degree lethal doses of physostigmine and also, respectively, of pentylenetetrazole and strychnine.
