376364-28-2Relevant academic research and scientific papers
Synthesis of chiral β-methyl tryptamine-derived GnRH antagonists
Simeone, Joseph P.,Bugianesi, Robert L.,Ponpipom, Mitree M.,Goulet, Mark T.,Levorse, Mark S.,Desai, Ranjit C.
, p. 6459 - 6461 (2007/10/03)
The stereospecific formation of 2-aryl-β-methyl tryptamine derivatives 15 and 16 from chiral 4-chloro-1-(3,5-dimethylphenyl)-3-methylbutanones is described. These intermediates were further manipulated into the GnRH antagonists 1b and 1c in five steps.
