376584-70-2Relevant academic research and scientific papers
A new series of potent benzodiazepine gamma-secretase inhibitors.
Churcher, Ian,Ashton, Kate,Butcher, John W,Clarke, Earl E,Harrison, Timothy,Lewis, Huw D,Owens, Andrew P,Teall, Martin R,Williams, Susie,Wrigley, Jonathan D J
, p. 179 - 183 (2007/10/03)
A new series of benzodiazepine-containing gamma-secretase inhibitors with potential use in the treatment of Alzheimer's disease is disclosed. Structure-activity relationships of the pendant hydrocinnamate side-chain which led to the preparation of highly
