376609-67-5Relevant academic research and scientific papers
Synthesis, electrochemical, thermal and photophysical characterization of photoactive discotic dyes based on the tris-[1,2,4]-triazolo-[1,3,5]-triazine core
Dal-Bó, Alexandre Gon?alves,Cisneros, Georgina Gisel López,Cercena, Rodrigo,Mendes, Jackson,da Silveira, Letícia Matos,Zapp, Eduardo,Domiciano, Kelvin Guessi,da Costa Duarte, Rodrigo,Rodembusch, Fabiano Severo,Frizon, Tiago Elias Allievi
, p. 49 - 56 (2016)
This work presents the synthesis and characterization of compounds based on the heterocycle tris-[1,2,4]-triazolo-[1,3,5]-triazine (TTT) obtained by a new building block that can be applied to afford different discotic materials in one step. The thermal p
Synthesis, X-ray characterization, Hirshfeld surface analysis and DFT calculations on tetrazolyl-phenol derivatives: H-bonds vs C–H…π/π…π interactions
Bibi, Asma,Khan, Imtiaz,Andleeb, Hina,Simpson, Jim,Tahir, Muhammad Nawaz,Hameed, Shahid,Frontera, Antonio
, (2020/10/20)
Tetrazoles are nitrogen rich heterocycles with a broad spectrum of medicinal properties and potential for use as drugs. A significant number of FDA approved drugs incorporate the tetrazole moiety indicating the versatile pharmaceutical potential associate
Side-chain liquid-crystalline polymer tetrazoles: Synthesis and characterization
Tariq, Muhammad,Hameed, Shahid,Magnago, Rachel F.,Bechtold, Ivan H.,Merlo, Aloir A.
, p. 1275 - 1282 (2014/08/05)
The synthesis and phase behavior of three new side-chain liquid crystal polymers with short and long flexible alkyl spacers are described. These new materials show smectic C (SmC) mesophase. X-ray analysis for two samples has revealed that SmC mesophase displays partial interdigitation for the polymer with short flexible spacer, while for long flexible spacer polymer no interdigitation was observed. ?2014 Sociedade Brasileira de Qui?mica.
Synthesis and characterization of some novel tetrazole liquid crystals
Tariq, Muhammad,Hameed, Shahid,Bechtold, Ivan H.,Bortoluzzi, Adailton J.,Merlo, Aloir A.
, p. 5583 - 5593 (2013/09/12)
The synthesis and characterization of new 4-[(2-alkyl)-2H-tetrazol-5-yl] phenyl 4-alkyloxybenzoates (5a-i) and 5-{4-[(4-substituted)benzyloxy]phenyl}-2- alkyl-2H-tetrazoles (7a-e) are reported. The reported tetrazoles contain two alkyl chains (six to ten
Zeolite and sulfated zirconia as catalysts for the synthesis of 5-substituted 1H-tetrazoles via [2+3] cycloaddition of nitriles and sodium azide
Teimouri, Abbas,Najafi Chermahini, Alireza
experimental part, p. 2606 - 2610 (2011/10/09)
The [2+3] cycloaddition between various nitriles and sodium azide proceeds smoothly in the presence of zeolite and sulfated zirconia as effective catalysts, in water and DMF/MeOH, to give the corresponding 5-substituted 1H-tetrazoles in good to high yields. The reaction most probably proceeds through the in situ formation of catalyst azide species, followed by a successive [2+3] cycloaddition with the nitriles. This method has the advantages of high yields, simple methodology and easy work-up. The catalyst can be recovered by simple filtration and reused with good yields.
Clay-catalyzed synthesis of 5-substituent 1-H-tetrazoles
Chermahini, Alireza Najafi,Teimouri, Abbas,Momenbeik, Fariborz,Zarei, Amin,Dalirnasab, Zeinab,Ghaedi, Aseyeh,Roosta, Mostafa
experimental part, p. 913 - 922 (2010/09/03)
In this study, the possibility of 5-substituted 1-H-tetrazoles synthesis using clays as catalyst was investigated. The reaction of a series of aromatic nitriles with sodium azide was catalyzed by montmorillonite K-10 or kaolin clays in water or DMF as solvent. Conventional heating or ultrasonic irradiation was used to promote reaction. The amount of nitrile to sodium azide mole ratio, amount of catalyst, reaction time, and solvent type were optimized. The versatility of this method was checked by using various nitriles, which showed reasonable yields of tetrazole formation. It was found that using nitriles with electron-with-drawing groups result in both higher yields and lower reaction times. The catalysts could be reused several times without significant loss of their catalytic activity. Compared to conventional heating, ultrasonic irradiation reduced reaction times and increased catalyst activity. The present procedure is green and offers advantages, such as shorter reaction time, simple workup, and recovery and reusability of catalyst.
