376637-85-3 Usage
General Description
3-Phenoxybenzylamine hydrochloride is a chemical compound that is commonly used in organic synthesis, particularly in the production of pesticides. It is derived from the organic compound phenoxybenzylamine and hydrochloric acid. 3-Phenoxybenzylamine hydrochloride is characterized by its white to off-white crystalline appearance and its solubility in water, which makes it easy to use in various chemical reactions. The reactions involving 3-Phenoxybenzylamine hydrochloride generally involve the displacement of the chlorine atom, leading to a wide array of possible end products. When handling this chemical, it is important to follow safety precautions due to its potential for irritation or harm when in contact with skin or eyes, or if ingested or inhaled.
Check Digit Verification of cas no
The CAS Registry Mumber 376637-85-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,7,6,6,3 and 7 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 376637-85:
(8*3)+(7*7)+(6*6)+(5*6)+(4*3)+(3*7)+(2*8)+(1*5)=193
193 % 10 = 3
So 376637-85-3 is a valid CAS Registry Number.
InChI:InChI=1/C13H13NO/c14-10-11-5-4-8-13(9-11)15-12-6-2-1-3-7-12/h1-9H,10,14H2
376637-85-3Relevant articles and documents
Rapid Continuous Ruthenium-Catalysed Transfer Hydrogenation of Aromatic Nitriles to Primary Amines
Labes, Ricardo,González-Calderón, Davir,Battilocchio, Claudio,Mateos, Carlos,Cumming, Graham R.,De Frutos, Oscar,Rincón, Juan A.,Ley, Steven V.
supporting information, p. 2855 - 2858 (2017/10/06)
A continuous flow method for the selective reduction of aromatic nitriles to the corresponding amine is reported. The method is based on a ruthenium-catalysed transfer-hydrogenation process, requires no additives, and uses isopropanol as both solvent and reducing agent. The process utilizes 1 mol% of the commercially available [Ru(p -cymene)Cl 2 ] 2, with a residence time of ca. 9 min, and a throughput of 50 mmol/h. The method was successfully applied to a range of aromatic nitriles providing the corresponding primary amines in good yields.