376642-41-0

Upstream product

• 71101-89-8 trans-4-butylcyclohexane carboxylic acid 
• 344411-87-6 methyl ester of 4-butylcyclohexanecarboxylic acid 

Downstream Products

• 71458-13-4 trans-4-n-butylcyclohexylmethyl bromide 

Relevant academic research and scientific papers

CYCLOALKYL-CONTAINING CARBOXYLIC ACIDS AND USES THEREOF

The present application discloses a compound of formula (I) or a salt thereof: (I) and compositions comprising such compound or salt thereof. The use of such compound, salt thereof or composition comprising same for treating anemia or leukopenia, fibrosis, cancer, hypertension and/or a metabolic condition in a subject is also disclosed.

Tyrosine phosphatase inhibitors

A compound of the formula (I): wherein X1 and X2 are the same or different and each is a bond or a spacer having 1 to 20 atom(s) in the main chain; one of R1 and R2 is a cycle group having substituent(s) selected from 1) an optionally substituted carboxy-C1-6 alkoxy group and 2) an optionally substituted carboxy-C1-6 aliphatic hydrocarbon group, wherein the cycle group optionally has additional substituent(s), and the other is an optionally substituted cycle group or a hydrogen atom; and R3, R4 and R5 are the same or different and each is a hydrogen atom or a substituent, or R4 may link together with R3 or R5 to form an optionally substituted ring; provided that when R3 is a hydrogen atom, R4 is a hydrogen atom and R5 is methyl, X2—R2 is not 4-cyclohexylphenyl; when R3 is 4-methoxyphenyl, R4 is a hydrogen atom and R5 is methyl, X2—R2 is not 4-methoxyphenyl; and when R1 or R2 is a hydrogen atom, the adjacent X1 or X2 is not a C1-7 alkylene; or a salt thereof exhibits a protein tyrosine phosphatase inhibitory action and is useful as a prophylactic or therapeutic agent for diabetes or the like.

1,3-dioxane derivative and liquid crystal compositions containing it

A 1,3-dioxane derivative and a liquid crystal composition containing it as expressed by the general formula STR1 (where R is a straight chain alkyl group of carbon number 1 to 10, A is a single bond or --CH2 CH2 -- group, n is 0 or 1, and the cyclohexane ring and 1,3-dioxane ring are respectively in trans form is disclosed.) The 1,3-dioxane derivative represented by general formula (I) has a very large dielectric anisotropy and a small birefringence. Liquid crystal compositions containing (I) can be driven at low voltage and will provide a liquid crystal display apparatus with a wide visual angle.

1,3-dioxane derivatives, methods of preparation and liquid crystal compositions including same

Trans-2-phenyl-5-trans-4'-alkylcyclohexyl-1,3-dioxane derivatives represented by the general formula: STR1 wherein R is a linear alkyl group of 1 to 10 carbon atoms, A is a single covalent bond or a --CH2 CH2 -- group, X is F or CN,

SYNTHESIS AND SOME PHYSICAL PROPERTIES OF PHENYL CYCLOHEXYL ETHYLENES.

Some series of trans-1-(4-substituted phenyl)-2(trans-4-n-alkylcyclohexyl) ethylenes, which show nematic phases, were prepared. Their transition temperatures, birefringences and bulk viscosities were measured. Their properties are compared with those of o