3770-60-3Relevant articles and documents
A 2 - [d] oxazole chlorobenzene and -5 - preparation of formic acid method (by machine translation)
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Paragraph 0020; 0025; 0026, (2017/12/27)
The invention discloses a 2 - chlorobenzene and [d] oxazole - 5 - carboxylic acid, in order to 2 - nitro - 4 - methyl phenol as the starting material, passes through the reduction, ring, chlorinated, oxidation to obtain the target product, the compound is an important medical intermediates. (by machine translation)
NOVEL MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS REPLICATION
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, (2009/10/31)
The embodiments provide compounds of the general Formulae I, II, III, IV, V, VI, VII, and X, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments further provide treatment methods, including methods of treating a hepatitis C virus infection and methods of treating liver fibrosis, the methods generally involving administering to an individual in need thereof an effective amount of a subject compound or composition.
Design and synthesis of highly potent and selective human peroxisome proliferator-activated receptor α agonists
Yamazaki, Yukiyoshi,Abe, Kazutoyo,Toma, Tsutomu,Nishikawa, Masahiro,Ozawa, Hidefumi,Okuda, Ayumu,Araki, Takaaki,Oda, Soichi,Inoue, Keisuke,Shibuya, Kimiyuki,Staels, Bart,Fruchart, Jean-Charles
, p. 4689 - 4693 (2008/02/11)
A combination of benzoxazole, phenoxyalkyl side chain, and phenoxybutyric acids was identified as a highly potent and selective human peroxisome proliferator-activated receptor α (PPARα) agonist. The synthesis, structure-activity relationship (SAR) studies, and in vivo activities of the representative compounds are described.