37704-45-3

Basic information

• Product Name: METHYL 7-HYDROXY-5-OXO-1,2,3,5-TETRAHYDROINDOLIZINE-8-CARBOXYLATE
• Synonyms: 8-Indolizinecarboxylic acid, 1,2,3,5-tetrahydro-7-hydroxy-5-oxo-, methyl ester
• CAS NO: 37704-45-3
• Molecular Formula: C₁₀H₁₁NO₄
• Molecular Weight: 209.2
• Mol File: 37704-45-3.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 362.6°C at 760 mmHg
• Flash Point: 173.1°C
• Appearance: /
• Density: 1.42g/cm³
• Vapor Pressure: 1.01E-06mmHg at 25°C
• Refractive Index: 1.605
• CAS DataBase Reference: METHYL 7-HYDROXY-5-OXO-1,2,3,5-TETRAHYDROINDOLIZINE-8-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 7-HYDROXY-5-OXO-1,2,3,5-TETRAHYDROINDOLIZINE-8-CARBOXYLATE(37704-45-3)
• EPA Substance Registry System: METHYL 7-HYDROXY-5-OXO-1,2,3,5-TETRAHYDROINDOLIZINE-8-CARBOXYLATE(37704-45-3)

Safety Data

• Hazardous Substances Data: 37704-45-3(Hazardous Substances Data)

Usage

InChI:InChI=1/C10H11NO4/c1-15-10(14)9-6-3-2-4-11(6)8(13)5-7(9)12/h5,13H,2-4H2,1H3

Upstream product

• 5264-35-7 2-methoxy-1-pyrroline 
• 1830-54-2 3-oxopentanedioic acid dimethyl ester 

Downstream Products

• 116993-50-1 10-carboxy-4-hydroxy-3-phenyl-8,9-dihydro-7H-pyranno<3,2-f>indolizin-2,5-dione 
• 116993-48-7 3-benzyl-4-hydroxy-8,9-dihydro-7H-pyranno<3,2-f>indolizin-2,5-dione 
• 116993-49-8 4-hydroxy-3-phenyl-8,9-dihydro-7H-pyranno<3,2-f>indolizin-2,5-dione 
• 58156-35-7 7-hydroxy-2,3-dihydro-1H-indolizin-5-one 
• 116993-47-6 4-hydroxy-10-methoxycarbonyl-3-phenyl-8,9-dihydro-7H-pyranno<3,2-f>indolizin-2,5-dione 

Relevant articles and documents

MAPK/ERK KINASE INHIBITORS

Compounds of the following formula are provided for use with MEK: wherein the variables are as defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.