377083-98-2 Usage
General Description
3-(4-Chloro-2-fluoro-phenyl)-propionic acid ethyl ester is a chemical compound with the molecular formula C12H12ClFO2. It is an ester of the propionic acid, and it contains a phenyl ring with a chlorine and fluoro substituent. 3-(4-CHLORO-2-FLUORO-PHENYL)-PROPIONIC ACID ETHYL ESTER is commonly used as a pharmaceutical intermediate and building block in the synthesis of various drugs. It has potential pharmacological properties and can be used as an analgesic, anti-inflammatory, and antipyretic agent. In addition, it may also have applications in the development of new drugs and medicinal research. However, the compound should be handled and used with caution due to its potential health and safety risks.
Check Digit Verification of cas no
The CAS Registry Mumber 377083-98-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,7,7,0,8 and 3 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 377083-98:
(8*3)+(7*7)+(6*7)+(5*0)+(4*8)+(3*3)+(2*9)+(1*8)=182
182 % 10 = 2
So 377083-98-2 is a valid CAS Registry Number.
InChI:InChI=1/C11H12ClFO2/c1-2-15-11(14)6-4-8-3-5-9(12)7-10(8)13/h3,5,7H,2,4,6H2,1H3
377083-98-2Relevant articles and documents
Indanylidenes. 2. Design and synthesis of (E)-2-(4-chloro-6-fluoro-1-indanylidene)-N-methylacetamide, a potent antiinflammatory and analgesic agent without centrally acting muscle relaxant activity
Musso, David L.,Orr, G. Faye,Cochran, Felicia R.,Kelley, James L.,Selph, Jeffrey L.,Rigdon, Greg C.,Cooper, Barrett R.,Jones, Michael L.
, p. 409 - 416 (2007/10/03)
Extension of the structure-activity relationship studies that led to the discovery of the nonsedating potent muscle relaxant, antiinflammatory, and analgesic agent (E)-2-(4,6-difluoro-1-indanylidene)acetamide, 1, has given rise to (E)-2-(4-chloro-6-fluoro