377091-22-0

Basic information

• Product Name: 3-[6-(benzyl-isopropyl-amino)-3-formyl-pyridin-2-yl]-3-(4-methoxy-2-trityloxymethyl-phenyl)-propionic acid tert-butyl ester
• Synonyms: 3-[6-(benzyl-isopropyl-amino)-3-formyl-pyridin-2-yl]-3-(4-methoxy-2-trityloxymethyl-phenyl)-propionic acid tert-butyl ester
• CAS NO: 377091-22-0
• Molecular Weight: 760.973
• Mol File: 377091-22-0.mol

Chemical Properties

• CAS DataBase Reference: 3-[6-(benzyl-isopropyl-amino)-3-formyl-pyridin-2-yl]-3-(4-methoxy-2-trityloxymethyl-phenyl)-propionic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[6-(benzyl-isopropyl-amino)-3-formyl-pyridin-2-yl]-3-(4-methoxy-2-trityloxymethyl-phenyl)-propionic acid tert-butyl ester(377091-22-0)
• EPA Substance Registry System: 3-[6-(benzyl-isopropyl-amino)-3-formyl-pyridin-2-yl]-3-(4-methoxy-2-trityloxymethyl-phenyl)-propionic acid tert-butyl ester(377091-22-0)

Safety Data

• Hazardous Substances Data: 377091-22-0(Hazardous Substances Data)

Upstream product

• 1026705-09-8 (E)-3-[6-(Benzyl-isopropyl-amino)-3-((4S,5S)-3,4-dimethyl-5-phenyl-oxazolidin-2-yl)-pyridin-2-yl]-acrylic acid tert-butyl ester 
• 377091-30-0 2-bromo-5-methoxybenzyl trityl ether 
• 377091-20-8 6-bromo-3-formyl-2-(N-isopropyl-N-benzylamino)pyridine 
• 377091-19-5 6-bromo-2-(N-isopropyl-N-benzylamino)pyridine 
• 66192-25-4 2-bromo-5-methoxybenzyl chloride 
• 76-84-6 triphenylmethyl alcohol 
• 626-05-1 2,6-Dibromopyridine 

Downstream Products

• 444987-47-7 2-(benzyl-isopropyl-amino)-5-(2,3-dihydro-benzofuran-6-yl)-7-(4-methoxy-2-trityloxymethyl-phenyl)-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid tert-butyl ester 

Relevant articles and documents

Practical asymmetric synthesis of a selective endothelin A receptor (ETA) antagonist

Equation presented A practical, chromotography-free asymmetric synthesis was developed for the large scale preparation of an endothelin receptor antagonist 2. This synthesis includes a new efficient process for the preparation of 6-bromo-2,3-dihydrobenzof