377092-72-3

Upstream product

• 204577-67-3 (1R)-2-endo-acetyl-2-exo-(trimethylsilyloxy)-1,7,7-trimethylbicyclo[2.2.1]heptane 
• 620-05-3 iodomethylbenzene 
• 377092-62-1 3-Phenyl-1-((1R,2R,4R)-1,7,7-trimethyl-2-trimethylsilanyloxy-bicyclo[2.2.1]hept-2-yl)-propan-1-one 

Relevant academic research and scientific papers

Alkylation of chiral α-hydroxy ketones derived from (1R)-(+)-camphor. An asymmetric variant of the classical acetylene route to carbonyl compounds

Equation presented The asymmetric version of the traditional route for transforming acetylene into α-branched carbonyl compounds is now feasible for the first time. The method involves the temporary attachment of camphor to acetylene and gives a remarkably high diastereo-and enantioselectivity.