3771-31-1 Usage
Description
4-[(6-methoxybenzothiazol-2-yl)azo]-N,N-dimethylaniline, commonly known as Methyl Orange, is an azo dye that serves as a pH indicator in titrations. It is a yellow to orange crystalline powder, which is insoluble in water but soluble in ethanol and dilute acids. With a molecular formula of C14H14N3NaO3S and a molecular weight of 327.33 g/mol, Methyl Orange is recognized for its color-changing properties in response to varying pH levels, making it a valuable tool in laboratory settings.
Uses
Used in Laboratory Applications:
Methyl Orange is used as a pH indicator in titrations for determining the acidity or alkalinity of a solution. Its color change, from yellow to orange, assists in identifying the pH levels accurately.
Used in Chemical Education:
In educational settings, Methyl Orange is utilized for teaching purposes, particularly in chemistry classes, to demonstrate the concept of pH and the use of indicators in acid-base titrations.
Used in Research:
Methyl Orange is also employed in various research applications, where its color-changing properties can be instrumental in studying pH-dependent reactions and processes.
Used in Analytical Chemistry:
In the field of analytical chemistry, Methyl Orange serves as a valuable tool for qualitative and quantitative analysis, helping to determine the endpoint of titrations and assess the concentration of acids or bases in a solution.
Check Digit Verification of cas no
The CAS Registry Mumber 3771-31-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,7,7 and 1 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 3771-31:
(6*3)+(5*7)+(4*7)+(3*1)+(2*3)+(1*1)=91
91 % 10 = 1
So 3771-31-1 is a valid CAS Registry Number.
InChI:InChI=1/C16H16N4OS/c1-20(2)12-6-4-11(5-7-12)18-19-16-17-14-9-8-13(21-3)10-15(14)22-16/h4-10H,1-3H3/b19-18+
3771-31-1Relevant articles and documents
Discovery of Small Molecules that Induce the Degradation of Huntingtin
Tomoshige, Shusuke,Nomura, Sayaka,Ohgane, Kenji,Hashimoto, Yuichi,Ishikawa, Minoru
supporting information, p. 11530 - 11533 (2017/09/11)
Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder caused by the aggregation of mutant huntingtin (mHtt), and removal of toxic mHtt is expected to be an effective therapeutic approach. We designed two small hybrid molecules (1 and 2) by linking a ligand for ubiquitin ligase (cellular inhibitor of apoptosis protein 1; cIAP1) with probes for mHtt aggregates, anticipating that these compounds would recruit cIAP1 to mHtt and induce selective degradation by the ubiquitin-proteasome system. The synthesized compounds reduced mHtt levels in HD patient fibroblasts and appear to be promising candidates for the development of a treatment for HD.
