37720-78-8Relevant academic research and scientific papers
Enzyme-catalysed transformations of ent-kaurane diterpenoids
Monsalve, Leandro N.,Rosselli, Sergio,Bruno, Maurizio,Baldessari, Alicia
, p. 2106 - 2115 (2007/10/03)
Several acetyl derivatives of linearol, atractyligenin and atractylitriol were obtained through enzyme-catalysed acetylation and deacetylation reactions. In most reactions lipases showed regio- and stereoselective behaviour, allowing a family of novel compounds to be prepared. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2005.
Biotransformation of the diterpenes epicandicandiol and candicandiol by Mucor plumbeus
Fraga, Braulio M.,Alvarez, Laura,Suarez, Sergio
, p. 327 - 331 (2007/10/03)
The microbiological transformation of the diterpene epicandicandiol (1) with Mucor plumbeus gave foliol (3), sideritriol (5), and 7β,16α,17,18-tetrahydroxy-ent-kaurane (7), while the incubation of candicandiol (2) gave 7α,9β,18-trihydroxy-ent-kaur-16-ene (10), canditriol (11), and 7α,16α,17,18-tetrahydroxy-entkaurane (12). Thus, the main difference observed in both feedings, resulting from the spatial change in the orientation of the 7-hydroxyl, from axial in the substrate 1 to equatorial in 2, was the formation of a 3α- and a 9β-hydroxylated derivative, respectively.
