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(2β,3β,14R)-2,3-Epoxygrayanotoxane-5,6β,10,14,16-pentol 14-acetate, commonly referred to as grayanotoxin, is a naturally occurring toxic diterpenoid compound found in plants of the Rhododendron genus. It is a member of the "mad honey" neurotoxins and is known for its ability to cause poisoning in humans and animals when ingested in excessive amounts. Grayanotoxin exerts its toxic effects by interacting with sodium channels in cell membranes, leading to a range of symptoms including dizziness, weakness, nausea, vomiting, and potentially life-threatening heart and respiratory failure in severe cases. Due to its potent toxicity, grayanotoxin is classified as a hazardous substance that requires careful handling and management.

37720-86-8

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37720-86-8 Usage

Uses

Used in Pharmaceutical Research:
Grayanotoxin is utilized in pharmaceutical research as a tool compound to study the function and modulation of sodium channels in cell membranes. Its ability to affect these channels provides valuable insights into the development of drugs targeting neurological disorders and pain management.
Used in Toxicological Studies:
As a potent neurotoxin, grayanotoxin is employed in toxicological studies to investigate the mechanisms of action and potential antidotes for poisoning caused by similar compounds. Understanding its effects on the body can contribute to the development of effective treatments and countermeasures in cases of accidental or intentional exposure.
Used in Analytical Chemistry:
Grayanotoxin serves as a reference compound in analytical chemistry for the development and validation of methods to detect and quantify toxic substances in various samples, such as food, plants, and environmental matrices. Its unique chemical structure and properties make it a suitable candidate for method development and quality control in analytical laboratories.
Used in Forensic Science:
In forensic science, grayanotoxin is used as a marker compound to identify and analyze cases of poisoning or contamination involving toxic plants or substances. Its presence in samples can provide crucial evidence in investigations related to criminal activities or accidental exposures.

Check Digit Verification of cas no

The CAS Registry Mumber 37720-86-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,7,7,2 and 0 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 37720-86:
(7*3)+(6*7)+(5*7)+(4*2)+(3*0)+(2*8)+(1*6)=128
128 % 10 = 8
So 37720-86-8 is a valid CAS Registry Number.
InChI:InChI=1/C22H34O7/c1-10(23)28-16-11-6-7-12-20(5,26)15-14-17(29-14)18(2,3)22(15,27)13(24)8-21(12,16)9-19(11,4)25/h11-17,24-27H,6-9H2,1-5H3

37720-86-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name Rhodojaponin V

1.2 Other means of identification

Product number -
Other names 5,6,10,16-tetrahydroxy-2,3-epoxygrayanotoxan-14-yl acetate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:37720-86-8 SDS

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