3776-44-1 Usage
General Description
2-(Naphthalen-1-yl)-3-phenylpropanoic acid, also known as Niflumic acid, is a non-steroidal anti-inflammatory drug (NSAID) that is used for the treatment of pain and inflammation. It works by inhibiting the production of certain chemicals in the body that cause pain and inflammation. Niflumic acid is commonly prescribed for conditions such as arthritis, menstrual cramps, and muscle pain. It is available in various forms including tablets and capsules and is typically taken orally. Like other NSAIDs, it may cause side effects such as stomach upset, heartburn, and dizziness, and should be used with caution in certain individuals, such as those with a history of stomach ulcers or kidney disease.
Check Digit Verification of cas no
The CAS Registry Mumber 3776-44-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,7,7 and 6 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 3776-44:
(6*3)+(5*7)+(4*7)+(3*6)+(2*4)+(1*4)=111
111 % 10 = 1
So 3776-44-1 is a valid CAS Registry Number.
3776-44-1Relevant articles and documents
GUANIDINE DERIVATIVES AS TRPC MODULATORS
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Page/Page column 43; 55, (2014/02/16)
The present invention is directed to guanidine derivatives as inhibitors of transient receptor potential canonical channels (TRPC channels), in particular TRPC3 and/or TRPC6 and/or TRPC7 activity, more particularly TRPC6 activity. Also provided herein are processes for preparing compounds described herein, intermediates used in their synthesis, pharmaceutical compositions thereof, and methods for treating or preventing diseases, conditions and/or disorders mediated by TRPC channels (Formula (I))
Reactions of β-nitrostyrenes with Grignard reagents
Yao, Ching-Fa,Chen, Wen-Chang,Lin, Yu-Mei
, p. 6339 - 6342 (2007/10/03)
α-Phenyl-β-nitrostyrene 1a and β-nitrostyrene 1b react with Grignard reagents to generate hydroxyimoyl halides 3 or nitrile oxides 4 after workup with ice cold concentrated aqueous HX acid solution. Carboxylic acids 5 are the only products isolated from 1b and products 3 or 4 are still obtained from 1a when concentrated sulfuric acid solution is used.
