377774-45-3Relevant academic research and scientific papers
Synthetic procedure for the preparation of novel potent and selective A3 adenosine receptor radioligands
Volpini,Costanzi,Lambertucci,Vittori,Cristalli
, p. 775 - 779 (2001)
2-Phenylethynyladenosine and its N6-methyl derivative were synthesized and evaluated in binding assays at human adenosine receptors stably transfected on CHO cells. Results showed that the N6-methyl-2-phenylethynyladenosine is endowe
N6-alkyl-2-alkynyl derivatives of adenosine as potent and selective agonists at the human adenosine A3 receptor and a starting point for searching A2B ligands
Volpini, Rosaria,Costanzi, Stefano,Lambertucci, Catia,Taffi, Sara,Vittori, Sauro,Klotz, Karl-Norbert,Cristalli, Gloria
, p. 3271 - 3279 (2007/10/03)
A series of N6-alkyl-2-alkynyl derivatives of adenosine (Ado) have been synthesized and evaluated for their affinity at human A1, A2, and A3 receptors and for their potency at A2B adenosine receptor s
