377780-16-0Relevant articles and documents
Speeding up heterogeneous catalysis with an improved highly reusable catalyst for the preparation of enantioenriched secondary alcohols
Sánchez-Carnerero, Esther M.,Sandoval-Torrientes, Rafael,Urieta-Mora, Javier,Moreno, Florencio,Maroto, Beatriz L.,de la Moya, Santiago
, p. 23 - 30 (2017)
A new catalytic heterogeneous system, very efficient and highly reusable, for the preparation of enantioenriched secondary alcohols through the addition of diethylzinc to benzaldehyde has been developed. This system is based on a chiral bis(hydroxyamide) ligand supported on crosslinked polystyrene. The catalyst has been shown to be very efficient, leading to the corresponding secondary alcohol with an enantiomeric excess of 93% in a time as short as 2?h and using just 4% of the heterogeneous catalyst and just 1.5 equivalents of the organozinc reagent. We have demonstrated that the new catalyst is very stable and can be efficiently recycled with no decrease in yield or enantioselectivity. The presented system has an unquestionable interest for the potential transfer of the reaction to the industry by using catalytic fluidized-bed reactors.
A Carbon Electrode Functionalized by a Tricopper Cluster Complex: Overcoming Overpotential and Production of Hydrogen Peroxide in the Oxygen Reduction Reaction
Thiyagarajan, Natarajan,Janmanchi, Damodar,Tsai, Yi-Fang,Wanna, Wondemagegn Hailemichael,Ramu, Ravirala,Chan, Sunney I.,Zen, Jyh-Myng,Yu, Steve S.-F.
supporting information, p. 3612 - 3616 (2018/03/05)
A study of the oxygen reduction reaction (ORR) on a screen printed carbon electrode surface mediated by the tricopper cluster complex Cu3(7-N-Etppz(CH2OH)) dispersed on electrochemically reduced carbon black, where 7-N-Etppz(CH2OH) is the ligand 3,3′-(6-(hydroxymethyl)-1,4-diazepane-1,4-diyl)bis(1-(4-ethyl piperazin-1-yl)propan-2-ol), is described. Onset oxygen reduction potentials of about 0.92 V and about 0.77 V are observed at pH 13 and pH 7 vs. the reversible hydrogen electrode, which are comparable to the best values reported for any synthetic copper complex. Based on half-wave potentials (E1/2), the corresponding overpotentials are about 0.42 V and about 0.68 V, respectively. Kinetic studies indicate that the trinuclear copper catalyst can accomplish the 4 e? reduction of O2 efficiently and the ORR is accompanied by the production of only small amounts of H2O2. The involvement of the copper triad in the O2 activation process is also verified.
Heterocyclic compounds, which are inhibitors of the enzyme DPP-IV
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, (2008/06/13)
The present invention relates to therapeutically active and selective inhibitors of the enzyme DPP-IV, pharmaceutical compositions comprising the compounds and the use of such compounds for and the manufacture of medicaments for treating diseases that are
