37786-06-4 Usage
Uses
Used in Pharmaceutical Industry:
11-Deoxy PGF2α is used as a pharmacological agent for its potent smooth muscle contraction properties. It is particularly useful in the development of drugs targeting conditions that involve smooth muscle dysfunction or require controlled muscle contraction for therapeutic effects.
Used in Research and Development:
In the field of biomedical research, 11-deoxy PGF2α serves as an important tool for studying the mechanisms of smooth muscle contraction and the role of prostaglandins in various physiological processes. Its enhanced potency compared to PGF2α makes it a valuable compound for investigating the underlying pathways and potential therapeutic targets for smooth muscle-related disorders.
Used in Veterinary Medicine:
11-Deoxy PGF2α is also utilized in veterinary medicine, where its potent smooth muscle contraction properties can be applied to treat or manage conditions in animals that involve smooth muscle dysfunction, such as respiratory or cardiovascular issues.
Check Digit Verification of cas no
The CAS Registry Mumber 37786-06-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,7,7,8 and 6 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 37786-06:
(7*3)+(6*7)+(5*7)+(4*8)+(3*6)+(2*0)+(1*6)=154
154 % 10 = 4
So 37786-06-4 is a valid CAS Registry Number.
37786-06-4Relevant academic research and scientific papers
A NEW SYNTHESIS OF (+/-)-11-DEOXYPROSTAGLANDINS
Fetizon, M.,Montaufier, M. T.,Rens, J.
, p. 201 - 220 (2007/10/02)
A synthesis of a (+/-)-11-deoxyprostaglandin F2α has been carried out from furfural and levulinic acid.The symmetrical key intermediate, diethyl 4,7-dioxodecanedioate, can easily be prepared from 5-furfurylidenelevulinic acid under acidic conditions.
Organocuprate Conjugate-addition-Enolate-alkylation Reactions: A New Synthesis of 11-Deoxyprostaglandins
Dixon, Andrew J.,Taylor, Richard J. K.,Newton, Roger F.
, p. 1407 - 1410 (2007/10/02)
A short synthesis of a key 11-deoxyprostaglandin precursor, 6β--cis-α-2-oxabicyclooctan-3-one (11), is reported.Important reactions in the synthesis include preparation of 2α-allyl-3β-oct-1-enyl>cyclopentanone (4) by an organocuprate conjugate-addition-enolate-alkylation reaction, regiospecific epoxidation-cyclisation of the alcohol (7) to give 6β-oct-1-enil>-3-hydroxymethyl-cis-α-2-oxabicyclooctane (9), and oxidative degradation of (9) with manganese dioxide to give 6β-oct-1-enyl)-cis-α-2-oxabicyclooctan-3-one (10).
Novel compounds of the 11-deoxyprostaglandin E3, R3α, and F3β series
-
, (2008/06/13)
This disclosure describes compounds of the 11-deoxyprostaglandin E2, F2α, F2β, E3, F3α, and F3β series having bronchodilator activity.
