9-fluoro-11beta-hydroxy-6alpha-methylpregn-4-ene-3,20-dione, also known as dexamethasone, is a synthetic corticosteroid medication with potent anti-inflammatory and immunosuppressive properties. It is derived from the chemical modification of natural corticosteroids and is characterized by the presence of a fluorine atom at the 9th position, a hydroxyl group at the 11th position, and a methyl group at the 6th position. These structural features contribute to its enhanced anti-inflammatory and immunosuppressive effects compared to other corticosteroids. Used in Pharmaceutical Industry: 9-fluoro-11beta-hydroxy-6alpha-methylpregn-4-ene-3,20-dione is used as an anti-inflammatory and immunosuppressive agent for the treatment of various conditions such as allergic disorders, skin conditions, arthritis, respiratory disorders, and certain types of cancer. Its potent anti-inflammatory action helps alleviate symptoms like pain, swelling, and redness, while its immunosuppressive properties suppress the immune system's overactive response, providing relief from autoimmune and inflammatory diseases. Used in Allergy Treatment: 9-fluoro-11beta-hydroxy-6alpha-methylpregn-4-ene-3,20-dione is used as an anti-allergic medication to treat allergic reactions and conditions such as allergic rhinitis, asthma, and atopic dermatitis. Its ability to suppress the immune system and reduce inflammation helps control the symptoms and prevent the progression of these allergic disorders. Used in Dermatological Applications: 9-fluoro-11beta-hydroxy-6alpha-methylpregn-4-ene-3,20-dione is used as a topical treatment for various skin conditions, including eczema, psoriasis, and dermatitis. Its potent anti-inflammatory and immunosuppressive effects help reduce skin inflammation, itching, and redness, promoting healing and improving the overall skin condition. Used in Arthritis Treatment: 9-fluoro-11beta-hydroxy-6alpha-methylpregn-4-ene-3,20-dione is used as an anti-inflammatory agent for the treatment of various forms of arthritis, such as rheumatoid arthritis and osteoarthritis. Its ability to reduce inflammation and suppress the immune system helps alleviate joint pain, swelling, and stiffness, improving the quality of life for arthritis patients. Used in Respiratory Disorders: 9-fluoro-11beta-hydroxy-6alpha-methylpregn-4-ene-3,20-dione is used as a treatment for respiratory disorders, such as chronic obstructive pulmonary disease (COPD) and asthma. Its anti-inflammatory and immunosuppressive properties help reduce airway inflammation, improve lung function, and alleviate respiratory symptoms. Used in Oncology: 9-fluoro-11beta-hydroxy-6alpha-methylpregn-4-ene-3,20-dione is used as an adjunct therapy in the treatment of certain types of cancer, particularly brain tumors and leukemia. Its immunosuppressive and anti-inflammatory effects can help control the growth and spread of cancer cells, as well as alleviate cancer-related symptoms.
The CAS Registry Mumber 378-38-1 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,7 and 8 respectively; the second part has 2 digits, 3 and 8 respectively. Calculate Digit Verification of CAS Registry Number 378-38: (5*3)+(4*7)+(3*8)+(2*3)+(1*8)=81 81 % 10 = 1 So 378-38-1 is a valid CAS Registry Number.
378-38-1SDS
SAFETY DATA SHEETS
According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition