37803-53-5

Usage

Type of alcohol

Secondary

Substituents

Phenyl and methyl groups attached to the carbon chain

Usage

Organic synthesis, potential pharmaceutical applications (drug development), antioxidant and anticancer properties

Importance

Valuable building block for the synthesis of various organic compounds in the field of chemistry.

Upstream product

• 536-74-3 phenylacetylene 
• 565-80-0 2,4-dimethylpentan-3-one 
• 6738-06-3 phenylethynylmagnesium bromide 
• 932-88-7 1-iodo-2-phenylethyne 
• 4440-01-1 lithium phenylacetylide 

Downstream Products

• 232932-76-2 bromomethyl-(1,1-diisopropyl-3-phenyl-prop-2-ynyloxy)-dimethyl-silane 
• 117552-48-4 E-5-phenyl-pent-2-en-4-ynoic acid ethyl ester 
• 501-65-5 diphenyl acetylene 

Relevant academic research and scientific papers

Unraveling factors leading to efficient norbornadiene-quadricyclane molecular solar-thermal energy storage systems

Developing norbornadiene-quadricyclane (NBD-QC) systems for molecular solar-thermal (MOST) energy storage is often a process of trial and error. By studying a series of norbornadienes (NBD-R2) doubly substituted at the C7-position with R = H, M

Mild and solvent-free alkynylation of ketones on the KF/alumina

The solvent-free alkynylation of various ketones on the surface of KF/alumina under mild conditions is described. Copyright Taylor & Francis, Inc.

Indium-mediated carbonyl alkynylation

Indium mediates a Barbier-type reaction between alkynyl halides and aldehydes or ketones to give secondary or tertiary propargyl alcohols. Secondary alcohols can be oxidised in situ according an Oppenauer process.

Solvent-free addition of ethynylbenzene to ketones

The addition of ethynylbenzene to ketones proceeded efficiently in the absence of a solvent to give tertiary alkynols in good yields.

5-Endo-Trig Radical Cyclizations of Bromomethyldimethylsilyl Diisopropylpropargylic Ethers. A Highly Diastereoselective Access to Functionalized Cyclopentanes

An efficient radical sequence involving a 5-exo-dig, a diastereoselective 1,5-H transfer, and a rarely observed in an all-carbon system 5-endo-trig cyclization allows the construction of cyclopentyl derivatives 2 bearing four controlled stereogenic center

Cesium hydroxide: A superior base for the catalytic alkynylation of aldehydes and ketones and catalytic alkenylation of nitriles

The efficient addition of terminal alkynes to aldehydes or ketones to give propargyl alcohols in yields of 66-96% can be achieved by activation with catalytic amounts of CsOH · H2O [Eq.(a)]. A CsOH-catalyzed addition of acetonitrile derivatives