378212-24-9

Basic information

• Product Name: 3-hydroxy-N-(3-methylpyridin-2-yl)-1-oxo-6,7-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-2-carboxamide
• Synonyms: 1H,5H-benzo[ij]quinolizine-2-carboxamide, 6,7-dihydro-3-hydroxy-N-(3-methyl-2-pyridinyl)-1-oxo-
• CAS NO: 378212-24-9
• Molecular Formula: C₁₉H₁₇N₃O₃
• Molecular Weight: 335.3566
• Mol File: 378212-24-9.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 568.6°C at 760 mmHg
• Flash Point: 297.7°C
• Density: 1.43g/cm³
• Vapor Pressure: 9.07E-14mmHg at 25°C
• Refractive Index: 1.707
• CAS DataBase Reference: 3-hydroxy-N-(3-methylpyridin-2-yl)-1-oxo-6,7-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-2-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-hydroxy-N-(3-methylpyridin-2-yl)-1-oxo-6,7-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-2-carboxamide(378212-24-9)
• EPA Substance Registry System: 3-hydroxy-N-(3-methylpyridin-2-yl)-1-oxo-6,7-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-2-carboxamide(378212-24-9)

Safety Data

• Hazardous Substances Data: 378212-24-9(Hazardous Substances Data)

Upstream product

• 1603-40-3 3-methylpyridin-2-ylamine 
• 84088-84-6 ethyl 1-hydroxy-3-oxo-6,7-dihydro-3H,5H-pyrido-[3,2,1-ij]quinoline-2-carboxylate 

Relevant articles and documents

4-Hydroxy-2-quinolones 148. Synthesis and antitubercular activity of 1-hydroxy-3-oxo-6,7-dihydro-3H,5H-pyrido[3,2,1-ij]quinoline-2-carboxylic acid N-R-amides

An improved method for the preparation of ethyl 1-hydroxy-3-oxo-6,7- dihydro-3H,5H-pyrido[3,2,1-ij]quinoline-2-carboxylate has been proposed and a series of hetarylamides has been synthesized from it. A comparative analysis has been carried out of the antitubercular activities of the synthesized compounds with the active structural analogs 4-hydroxy-2-oxo-1,2-dihydroquinoline-3 and 1-hydroxy-3-oxo-5,6-dihydro-3H-pyrrolo[3,2,1-ij]quinoline-2-carboxamides studied before.