378248-22-7Relevant academic research and scientific papers
Asymmetric Heck cyclization route to indolizidine and azaazulene alkaloids: Synthesis of (+)-5-epiindolizidine 167B and indolizidine 223AB
Kiewel, Kurt,Tallant, Mathew,Sulikowski, Gary A.
, p. 6621 - 6623 (2001)
Asymmetric intramolecular Heck cyclization of endocyclic enamides occurs at room temperature to give indoloizidine and azaazulene ring systems in up to 86% enantiomeric excess. A synthesis of (+)-epiindolizidine 167B and formal synthesis of 5E,9Z-indolizidine 223AB is described.
