3785-87-3

Usage

Uses

Used in Pharmaceutical Industry:
(2E)-2-cyano-3-[4-(dimethylamino)phenyl]prop-2-enamide is used as an antihistamine and calcium channel blocker for treating symptoms of motion sickness, vertigo, and dizziness. It works by blocking histamine and calcium channels in the inner ear, which helps to reduce the symptoms of nausea and vomiting associated with motion sickness.
Used in Treatment of Meniere's Disease and Vestibular Disorders:
(2E)-2-cyano-3-[4-(dimethylamino)phenyl]prop-2-enamide is also used to treat symptoms of Meniere's disease and other vestibular disorders. It is typically administered orally in tablet form to provide relief from the symptoms.

Upstream product

• 100-10-7 4-dimethylamino-benzaldehyde 
• 21689-52-1 aminomethylene cyanacetamide 
• 107-91-5 cyanoacetic acid amide 

Downstream Products

• 141811-33-8 2-Amino-4-(4-dimethylamino-phenyl)-5,6,7,8,9,10-hexahydro-benzocyclooctene-1,3-dicarbonitrile 
• 141811-27-0 2-Amino-4-(4-dimethylamino-phenyl)-6,7,8,9-tetrahydro-5H-benzocycloheptene-1,3-dicarbonitrile 

Relevant academic research and scientific papers

5-Phenyl-1,2,3,4-tetrahydronaphthalene derivatives: Synthesis, spectroscopic and electrochemical investigation

A series of novel dyes, whose structures are based on 5-phenyl-1,2,3,4- tetrahydronaphthalene skeleton have been fully synthesized and characterized. The dyes were prepared in two-stage synthesis reaction. The 2-cyano-3-[4- aminophenyl]-2-propenamide deri

Condensation reactions of aromatic aldehydes with active methylene compounds catalyzed by alkaline ionic liquid

The Knoevenagel condensation reactions of aromatic aldehydes with active methylene compounds catalyzed by the functionalized ionic liquid, 1-n-butyl-3-methylimmidazolium hydroxide ([bmim]OH), were carried out under grinding, heating, and microwave irradia

Cyanovinylheteroaromatics for Organic Nonlinear Optics

Effects of various substituents including chromophores on the second harmonic generation (SHG) of cyanovinylheteroaromatics were examined.The molecular polarizability was calculated by the PPP MO method to correlate SHG responsiveness with chemical structures. 3-indole 8b exhibited good SHG efficiency (PE = 25U).The X-ray analysis of 8b showed that the crystals belong to novel and the most favorable P1 space group.