3786-46-7

Usage

Uses

Used in Pharmaceutical Industry:
3,6-Dihydroxyphthalic acid is used as a reactant in the preparation of (±)-fredericamycin A, a potent antitumor antibiotic. It plays a crucial role in the synthesis of this therapeutic compound, which has shown significant potential in the treatment of various types of cancer. The presence of the two hydroxyl groups in the molecule allows for the formation of essential chemical bonds and interactions with other molecules during the synthesis process.
Used in Chemical Synthesis:
3,6-Dihydroxyphthalic acid is also used as a building block in the synthesis of various organic compounds, including dyes, pigments, and polymers. Its unique structure and reactivity make it a valuable intermediate in the production of a wide range of chemical products. The hydroxyl groups present in the molecule facilitate the formation of ester, ether, and other functional groups, which can be further modified to create a diverse array of compounds with specific properties and applications.
Used in Research and Development:
Due to its versatile chemical properties, 3,6-dihydroxyphthalic acid is often employed in research and development for the discovery and optimization of new chemical entities. It serves as a key starting material for the synthesis of novel compounds with potential applications in various fields, such as pharmaceuticals, materials science, and environmental chemistry. 3,6-DIHYDROXYPHTHALIC ACID's ability to form a wide range of derivatives makes it an attractive candidate for exploring new chemical reactions and developing innovative synthetic strategies.

InChI:InChI=1/C8H6O6/c9-3-1-2-4(10)6(8(13)14)5(3)7(11)12/h1-2,9-10H,(H,11,12)(H,13,14)

Upstream product

• 2289-36-3 1,4-diacetoxy-9,10-anthraquinone 
• 861615-23-8 3-hydroxy-6-iodo-phthalic acid 
• 475-38-7 5,8-Dihydroxy-1,4-naphthoquinone 
• 68218-49-5 3,4,6-triiodo-phthalic acid-anhydride 
• 4733-50-0 2,3-dicyano-1,4-hydroquinone 
• 106-51-4 p-benzoquinone 
• 490-79-9 2,5-dihydroxybenzoic acid. 
• 695-99-8 2-Chloro-1,4-benzoquinone 
• 3958-79-0 methyl 3,6-dioxocyclohexa-1,4-diene-1-carboxylate 
• 2150-46-1 Methyl 2,5-dihydroxybenzoate 

Downstream Products

• 65489-47-6 dimethyl 3,6-dimethoxyphthalate 
• 116314-76-2 3,4-dihydroxy-phthalic acid-anhydride 
• 14597-12-7 3,6-dimethoxyphthalic anhydride 
• 123-31-9 hydroquinone 
• 124511-82-6 3,6-diacethoxyphthalic anhydride 
• 488-48-2 tetrabromobenzoquinone 
• 77220-15-6 dimethyl 3,6-dioxocyclohexa-1,4-diene-1,2-dicarboxylate 
• 103548-64-7 dimethyl 3,4,6-trihydroxyphthalate 
• 105518-06-7 dimethyl 3,4,6-triacetoxyphthalate 
• 1459157-11-9 2-(1-hydroxyheptyl)-3-(hydroxymethyl)benzene-1,4-diol 

Relevant academic research and scientific papers

A direct assay of butyrylcholinesterase activity using a fluorescent substrate

In this study, we report a direct fluorometric assay for butyrylcholinesterase (BChE) activity and screening of its inhibitor, using a fluorescent substrate. 2-(2-(5,6-Dimethoxy-1,3-dioxoisoindolin-2-yl)acetoxy)-N,N,N-trimethylethan-1-ammonium iodide (1)

Total Synthesis of Violaceoid A and (-)- and (+)-Violaceoid B

The first total synthesis of violaceoid A, a cytotoxic agent, and the asymmetric total synthesis of (-)- and (+)-violaceoid B are reported. The precursor was accessed by desymmetrization of a substituted quinol moiety, and the racemic secondary alcohol wa

Method for preparing 3,6-dihydroxyphthalimide

The invention discloses a method for preparing 3,6-dihydroxyphthalimide. According to the method disclosed by the invention, the 3,6-dihydroxyphthalimide is obtained by taking 3,6-dihydroxyphthalonitrile, acetic anhydride and urea as main raw materials through three steps of reaction. The method provided by the invention has the advantages that a process is simple, convenient and stable to operate; a product of each step is easy to separate, has high yield and is environmentally friendly and the comprehensive yield is 85 percent or more; the raw materials are cheap and easy to obtain and the production cost is greatly reduced so that industrial large-scale production is facilitated.

Fluorescence emissions of imide compounds and end-capped polyimides enhanced by intramolecular double hydrogen bonds

The structure and optical properties of a newly synthesized imide compound (DHNHPI) that forms intramolecular double hydrogen bonds (intra-HBs) were investigated. This compound exhibits intense absorption at 372 nm (Pdbl = 5091 cm-1 M-1/s

Inclusion complex containing epoxy resin composition for semiconductor encapsulation

The invention is an epoxy resin composition for sealing a semiconductor, including (A) an epoxy resin and (B) a clathrate complex. The clathrate complex is one of (b1) an aromatic carboxylic acid compound, and (b2) at least one imidazole compound represented by formula (II): wherein R2 represents a hydrogen atom, C1-C10 alkyl group, phenyl group, benzyl group or cyanoethyl group, and R3 to R5 represent a hydrogen atom, nitro group, halogen atom, C1-C20 alkyl group, phenyl group, benzyl group, hydroxymethyl group or C1-C20 acyl group. The composition has improved storage stability, retains flowability when sealing, and achieves an effective curing rate applicable for sealing delicate semiconductors.

Synthetic studies on the CDEF ring system of lactonamycin

Both (1) furan-maleimide Diels-Alder cycloaddition reaction and (2) furan-benzyne cycloaddition, Suzuki cross-coupling, boron-mediated aldol, and electrophilic aromatic substitution reactions were examined for the construction of the CDEF ring system of l