3787-46-0 Usage
Chemical class
Indole alkaloids
Explanation
1,3,4,7,12,12b-hexahydroindolo[2,3-a]quinolizin-6(2H)-one belongs to a group of naturally occurring organic compounds that contain an indole nucleus and are derived from the amino acid tryptophan.
Explanation
The compound has a complex structure consisting of two fused rings, one with six atoms and the other with five atoms, which are interconnected.
Explanation
A carbonyl group (C=O) is present at the 6th position of the compound, which is characteristic of ketones.
4. Pharmacological and biological activities
Explanation
The compound has potential applications in the field of medicine due to its pharmacological and biological properties, which are being studied for their effects on various biological systems.
Explanation
1,3,4,7,12,12b-hexahydroindolo[2,3-a]quinolizin-6(2H)-one is used as a starting material in the synthesis of various pharmaceuticals and natural products, due to its unique structure and reactivity.
Explanation
The compound's unique structure and potential biological properties make it an attractive target for researchers working in the fields of medicinal chemistry and drug discovery, as it may lead to the development of new therapeutic agents.
Explanation
The stability of the compound under various conditions (e.g., temperature, pH, light exposure) may be a factor to consider, as some compounds with complex structures can be sensitive to changes in their environment.
Explanation
The synthesis of 1,3,4,7,12,12b-hexahydroindolo[2,3-a]quinolizin-6(2H)-one likely involves a multi-step process, which may include the formation of the fused ring system, introduction of functional groups, and subsequent modifications to achieve the desired structure.
Explanation
Various analytical techniques, such as nuclear magnetic resonance (NMR), mass spectrometry, and X-ray crystallography, can be employed to study the structure, properties, and interactions of 1,3,4,7,12,12b-hexahydroindolo[2,3-a]quinolizin-6(2H)-one.
Structure
Cyclic compound with a six-membered ring fused to a five-membered ring
Ketone group
Position 6
Precursor in synthesis
Pharmaceutical and natural products
Interest to researchers
Medicinal chemistry and drug discovery
Solubility
May vary depending on the specific compound
Stability
May be sensitive to certain conditions
Synthesis
Multi-step process
Analytical techniques
NMR, mass spectrometry, and X-ray crystallography
Check Digit Verification of cas no
The CAS Registry Mumber 3787-46-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,7,8 and 7 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 3787-46:
(6*3)+(5*7)+(4*8)+(3*7)+(2*4)+(1*6)=120
120 % 10 = 0
So 3787-46-0 is a valid CAS Registry Number.
3787-46-0Relevant academic research and scientific papers
King, Frank D.
, p. 1459 - 1463 (2007)
(Chemical Equation Presented) A three-step synthesis of (±)-harmacine is described from the readily available 4,4-diethoxybutan-1-amine via an acid-mediated acyl iminium ion cyclisation. The synthesis of the homologous (±)1,2,3,4,6,7,12,12b-octahydroindole[2,3-a] quinolizine from 5,5-diethoxypentan-1-amine is also described. Although similar, the two systems required very different cyclisation conditions.
Synthesis of 6-Oxo-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizine
Tompkins, David C.,Reilly, Laurence W.,Nelson, Randall B.,Dolby, Lloyd J.,Gribble, Gordon W.
, p. 1048 - 1052 (2018/04/24)
An efficient synthesis of 6-oxo-1,2,3,4,5,7,12,12b-octahydroindolo[2,3-α]quinolizine from 2-acetylpyridine and phenylhydrazine is described. This derivative of the natural alkaloid desbromoarborescidine A is an important entry point to the sarpagine-vobas
