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(4-CHLORO-5-METHYL-3-TRIFLUOROMETHYL-PYRAZOL-1-YL)-ACETIC ACID, commonly referred to as CMTPA, is a versatile chemical compound that belongs to the pyrazole class. It is a derivative of acetic acid, characterized by the presence of a pyrazole ring with a chlorine atom at the 4th position, a methyl group at the 5th position, and a trifluoromethyl group at the 3rd position. The unique structure and functional groups of CMTPA make it a valuable compound for various applications in chemical and pharmaceutical industries.

378758-70-4

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378758-70-4 Usage

Uses

Used in Organic Synthesis:
CMTPA is used as a building block in organic synthesis for the creation of various complex organic molecules. Its unique functional groups allow for versatile chemical reactions, making it a valuable component in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
CMTPA is used as a pharmaceutical intermediate, playing a crucial role in the development of new drugs. Its unique structure and functional groups can be utilized to modify the properties of drug candidates, potentially enhancing their efficacy, selectivity, and pharmacokinetics.
Used in Research and Development:
CMTPA is used as a research chemical for studying the properties and reactivity of pyrazole derivatives. Its unique structure provides insights into the behavior of similar compounds, aiding in the discovery of new chemical reactions and the development of novel synthetic routes.

Check Digit Verification of cas no

The CAS Registry Mumber 378758-70-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,7,8,7,5 and 8 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 378758-70:
(8*3)+(7*7)+(6*8)+(5*7)+(4*5)+(3*8)+(2*7)+(1*0)=214
214 % 10 = 4
So 378758-70-4 is a valid CAS Registry Number.
InChI:InChI=1/C7H6ClF3N2O2/c1-3-5(8)6(7(9,10)11)12-13(3)2-4(14)15/h2H2,1H3,(H,14,15)

378758-70-4Relevant academic research and scientific papers

ANTAGONISTS OF CHEMOKINE RECEPTORS

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, (2014/03/24)

Compounds are provided that act as potent antagonists of the CCR1 receptor, and have in vivo anti-inflammatory activity. The compounds are generally aryl piperazine derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR1-mediated diseases, and as controls in assays for the identification of competitive CCR1 antagonists.

Thiazole-4-Carboxylic Acid Esters and Thioesters as Plant Protection Agents

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Page/Page column 29, (2011/05/08)

The use of thiazole-4-carboxylic esters and thioesters of the formula (I) in which R1, R2, R3, R4, R5, R6, R7, Y1, Y2, Y3, W, X and G have the me

1-ARYL-4-SUBSTITUTED PIPERAZINES DERIVATIVES FOR USE AS CCR1 ANTAGONISTS FOR THE TREATMENT OF INFLAMMATION AND IMMUNE DISORDERS

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Page 76, (2008/06/13)

Compounds are provided that act as potent antagonists of the CCR1 receptor, and which have been further confirmed in animal testing for inflammation, one of the hallmark disease states for CCR1. The compounds are generally aryl piperazine derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR1-mediated diseases, and as controls in assays for the identification of competitive CCR1 antagonists.

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