378784-04-4Relevant articles and documents
Isonucleosides incorporating universal bases
Nair,Sosnouski,Zhu
, p. 735 - 738 (2001)
Enantiomeric isodideoxynucleosides of the (S,S) and (R,R) families with the universal base, imidazole-4-carboxamide as the nucleobase, were synthesized as biological mimics of anti-HIV active D- and L-related isodideo-xyadenosines. In vitro anti-HIV evaluation in CEM cells of these target compounds showed that they were inactive. Further antiviral studies are in progress.