37928-23-7 Usage
Description
Benzenepropanoic acid, 2-chloro-.alpha.-oxo-, also known as 2-Chloro-2-oxo-2-phenylacetic acid, is a chemical compound with the molecular formula C9H7ClO3. It is a derivative of phenylacetic acid, which is commonly found in various plants and microorganisms. Benzenepropanoic acid, 2-chloro-.alpha.-oxofeatures a benzene ring, providing aromatic properties, and a chlorine atom attached to the alpha carbon, which imparts distinct reactivity and biological activity. Due to its potential health hazards and environmental impacts, it is important to handle this compound with caution.
Uses
Used in Pharmaceutical Industry:
Benzenepropanoic acid, 2-chloro-.alpha.-oxois used as a building block in the synthesis of pharmaceuticals for its distinct reactivity and biological activity. It contributes to the development of various drugs by serving as a key intermediate in chemical reactions, allowing for the creation of a wide range of medicinal compounds.
Used in Agrochemical Industry:
In the agrochemical industry, Benzenepropanoic acid, 2-chloro-.alpha.-oxois utilized as a precursor in the production of various agrochemicals. Its unique chemical structure allows it to be incorporated into the synthesis of pesticides, herbicides, and other agricultural chemicals, enhancing their effectiveness and selectivity in controlling pests and weeds.
Check Digit Verification of cas no
The CAS Registry Mumber 37928-23-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,7,9,2 and 8 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 37928-23:
(7*3)+(6*7)+(5*9)+(4*2)+(3*8)+(2*2)+(1*3)=147
147 % 10 = 7
So 37928-23-7 is a valid CAS Registry Number.
37928-23-7Relevant articles and documents
Kinetic and solvent isotope effects on biotransformation of aromatic amino acids and their derivatives
Kańska, Marianna,Jemielity, Jacek,Paj?k, Ma?gorzata,Pa?ka, Katarzyna,Podsadni, Katarzyna,Winnicka, El?bieta
, p. 627 - 634 (2016/12/26)
Aromatic amino acids such as l-phenylalanine, l-tryptophan, 3′,4′-dihydroxy-l-phenylalanine (l-DOPA), and their derivatives 3′,4′-dihydroxyphenylacelaldehyde (DOPAL) and 3′,4′-dihydroxyphenylethanol (DOPET), play an essential role in human metabolic processes. Incorrect or slow biotransformation of these compounds leads to some metabolic dysfunctions and in some cases to some neurodegenerative diseases. Therefore, studies of the biotransformation mechanisms of these metabolites draw biochemists' and medical researchers' attention. This study investigates the mechanisms of biotransformation of the aforementioned compounds using kinetic (KIE) and solvent (SIE) isotope effect methods. The overview presents the results and the numerical values of KIE and SIE methods, obtained in the study of biotransformation of l-phenylalanine, 5′-chloro-l-tryptophan, and l-DOPA, catalyzed by the enzymes from the lyases group (phenylalanine ammonia lyase, tryptophan indole-lyase, and tyrosine decarboxylase). Deuterium KIE was also determined during the deamination of 2′-chloro-l-phenylalanine in the presence of the enzyme l-phenylalanine dehydrogenase, as well as in the conversion of DOPAL into DOPET catalyzed by the enzyme alcohol dehydrogenase. The values of KIE and SIE have been determined using a noncompetitive spectrophotometric and a competitive (combined with internal radioactivity standard) radiometric methods.
