37940-49-1

Basic information

• Product Name: diethyl (3,5-dimethyl-4-hydroxybenzyl)phosphonate
• Synonyms: diethyl (3,5-dimethyl-4-hydroxybenzyl)phosphonate
• CAS NO: 37940-49-1
• Molecular Weight: 272.281
• Mol File: 37940-49-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: diethyl (3,5-dimethyl-4-hydroxybenzyl)phosphonate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl (3,5-dimethyl-4-hydroxybenzyl)phosphonate(37940-49-1)
• EPA Substance Registry System: diethyl (3,5-dimethyl-4-hydroxybenzyl)phosphonate(37940-49-1)

Safety Data

• Hazardous Substances Data: 37940-49-1(Hazardous Substances Data)

Upstream product

• 576-26-1 2.6-dimethylphenol 
• 42900-95-8 4-[(dimethylamino)methyl]-2,6-dimethylphenol 
• 74-88-4 methyl iodide 

Relevant articles and documents

Alpha-substituted beta-aminoethyl phosphonate derivatives

The present invention relates to novel α-substituted-β-aminoethylphosphonate and α-substituted-β-aminovinylphosphonate derivatives and their uses for lowering plasma levels of apo (a), Lp(a), apo B, apo B associated lipoproteins (low density lipoproteins

Process for the preparation of hydroxybenzylphosphonates

A process for the preparation of compounds of the general formula I STR1 in which R1 is hydrogen or methyl, R2 and R3 independently of one another are C1 -C18 alkyl, C5 -C8 cycloalkyl, phenyl, C7 -C9 phenylalkyl or halogen, R2 is additionally hydrogen and R7 and R8 independently of one another are C1 -C18 alkyl, phenyl or C7 -C18 alkylphenyl, which comprises reacting a phenol of the formula II STR2 in which R1 to R3 have the meaning described above, with formaldehyde or paraformaldehyde, an amine of the formula III in which R4 is C1 -C4 alkyl and R5 and R6 independently of one another are hydrogen or C1 -C4 alkyl, and a phosphite of the formula IV STR3 in which R7 and R8 have the meaning described above and R9 has the meaning given for R7 and R8, at a temperature of 0°-200° C. Some compounds of the formula I are novel.