3796-87-0Relevant academic research and scientific papers
A domino amidation route to indolines and indoles: Rapid syntheses of anhydrolycorinone, hippadine, oxoassoanine, and pratosine
Ganton, Michael D.,Kerr, Michael A.
, p. 4777 - 4779 (2007/10/03)
(Chemical Equation Presented) When subjected to palladium-catalyzed amidation conditions, 2-triflyloxy phenethyl carbonates undergo, in addition to the expected aryl cross-coupling, an additional amidation with net displacement of the carbonate. The result is a one-step synthesis of indolines which may be oxidized to indoles. The utility of the procedure is illustrated by the two- or three-step syntheses of anhydrolycorinone, hippadine, oxoassoanine, and pratosine.
Structure-activity relationships for inhibition of inosine monophosphate dehydrogenase by nuclear variants of mycophenolic acid
Nelson, Peter H.,Carr, Stephen F.,Devens, Bruce H.,Eugui, Elsie M.,Franco, Fidencio,Gonzalez, Carlos,Hawley, Ronald C.,Loughhead, David G.,Milan, David J.,Papp, Eva,Patterson, John W.,Rouhafza, Sussan,Sjogren, Eric B.,Smith, David B.,Stephenson, Rebecca A.,Talamas, Francisco X.,Waltos, Ann-Marie,Weikert, Robert J.,Wu, John C.
, p. 4181 - 4196 (2007/10/03)
Structure-activity relationships in the region of the phthalide ring of the inosine monophosphate dehydrogenase inhibitor mycophenolic acid have been explored. Replacement of the lactone ring with other cyclic moieties resulted in loss of potency, especia
929. Chrom-3-en-6-ols. The action of pyridine on alk-2-enyl-benzoquinones
McHale,Green
, p. 5060 - 5064 (2007/10/08)
Allylbenzoquinones are converted by treatment with pyridine into quinols and chrom-3-en-6-ols. The tendency for the latter reaction to occur increases as the benzoquinone ring becomes more highly substituted.
