37994-82-4 Usage
Uses
Used in Research and Diagnostics:
7-HYDROXYBENZO(A)PYRENE is used as a biomarker for [application reason] to identify exposure to tobacco smoke and its carcinogenic components. [application type] This helps in understanding the risk factors and potential health implications for individuals exposed to such environments.
Used in Environmental Monitoring:
7-HYDROXYBENZO(A)PYRENE is used as a contaminant indicator for [application reason] to monitor the presence of harmful pollutants in the environment, particularly in areas with high tobacco smoke exposure. [application type] This aids in assessing the environmental impact of tobacco smoke and implementing necessary measures to reduce its harmful effects.
Used in Pharmaceutical Development:
7-HYDROXYBENZO(A)PYRENE is used as a compound of interest for [application reason] in the development of new drugs and therapies targeting lung cancer and other tobacco-related diseases. [application type] Its unique properties and understanding of its metabolic pathways can contribute to the creation of more effective treatments for these conditions.
Used in Public Health Policies:
7-HYDROXYBENZO(A)PYRENE is used as a data point for [application reason] in formulating public health policies and regulations aimed at reducing tobacco smoke exposure and its associated health risks. [application type] This information can be crucial in creating awareness and driving initiatives to improve public health and reduce the prevalence of tobacco-related diseases.
Safety Profile
Questionable carcinogen withexperimental tumorigenic and neoplastigenic data by skincontact. Human mutation data reported. When heated todecomposition it emits acrid smoke and fumes.
Check Digit Verification of cas no
The CAS Registry Mumber 37994-82-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,7,9,9 and 4 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 37994-82:
(7*3)+(6*7)+(5*9)+(4*9)+(3*4)+(2*8)+(1*2)=174
174 % 10 = 4
So 37994-82-4 is a valid CAS Registry Number.
InChI:InChI=1/C20H12O/c21-18-6-2-5-15-16-10-9-13-4-1-3-12-7-8-14(11-17(15)18)20(16)19(12)13/h1-11,21H
37994-82-4Relevant academic research and scientific papers
Tetrabutylammonium Hydroxide: A Reagent for the Base-Catalyzed Dehydration of Vicinal Dihydro Diols of Aromatic Hydrocarbons. Implications to Ion-Pair Chromatography
McCourt, David W.,Roller, Peter P.,Gelboin Harry V.
, p. 4157 - 4161 (2007/10/02)
Vicinal dihydro diols of benzopyrene and benzanthracene are dehydrated to their phenolic derivatives by the methanol eluate of reverse-phase (octadecylsilane) columns previously treated with tetrabutylammonium phosphate.Phenols are also produced by treating the dihydro diols with methanolic tetrabutylammonium hydroxide on removal solvent.In most cases the regioselectivity is markedly different from the acid-catalyzed dehydration.The in situ generated tetrabutylammonium phenoxides are converted to the butyl ethers at high temperatures (150 deg C) but not under th e conditions of dehydration (60 deg C).Tetraethylammonium and tetramethylammonium hydroxides also dehydrate dihydro diols, whereas potassium and sodium hydroxides do not.Dehydration does occur by treatment of dihydro diols with potassium hydroxide in the presence of 1,4,7,10,13,16-hexaoxacyclooctadecane (18-crown-6) and with sodium methoxide in the presence of tetrabutylammonium chloride.A mechanism is suggested.
