380194-46-7

Upstream product

• 769-42-6 1,3-dimethylbarbituric acid 
• 874-42-0 2,4-dichlorobenzaldeyhde 
• 109-77-3 malononitrile 
• 67-52-7 BARBITURIC ACID 
• 41949-07-9 6-hydroxy-1,3-dimethyluracil 

Relevant academic research and scientific papers

Synthesis of pyrano[2,3‐d]pyrimidines and pyrido[2,3‐d]pyrimidines in the magnetized deionized water based on UV–visible study

Abstract: A green synthetic route to the facile one-pot multicomponent synthesis of pyrano[2,3‐d]pyrimidines and pyrido[2,3‐d]pyrimidines have been developed using magnetized deionized water (MDW) as a green solvent under catalyst-free conditions. All rea

Nano-Zn[2-boromophenylsalicylaldiminemethylpyranopyrazole]Cl2 as a novel nanostructured Schiff base complex and catalyst for the synthesis of pyrano[2,3-d]pyrimidinedione derivatives

Nano-Zn[2-boromophenylsalicylaldiminemethylpyranopyrazole]Cl2 (nano-[Zn-2BSMP]Cl2) as a novel nanostructured Schiff base complex was prepared and characterized using several techniques. Nano-[Zn-2BSMP]Cl2 was used as an ef

Introducing an effective nanocatalytic for the one-pot synthesis and investigation of biological properties of pyranopyrimidinone and xanthene derivatives

In this study, an effective method for the synthesis of pyranopyrimidinone and xanthene derivatives is introduced. In this method, zinc oxide-chitosan nanocomposite has been used as a catalyst and all reactions were performed under irradiated in a microwa

Nano-basic silica as an efficient catalyst for the multi-component preparation of pyrano[2,3-d]pyrimidine derivatives

A high-yield protocol is explored for the synthesis of pyrano[2,3-d]pyrimidines through the multi-component reaction of aromatic aldehydes, 1,3-Dimethylbarbituric acid, and malononitrile using nano-basic silica as an efficient catalyst. The method tolerat

Synthesis and characterization of novel magnetic nanoparticles supported imidazole ion as an efficient catalytic system for the three-component reaction of arylaldehydes, malononitrile and a-hydroxy or a-amino active methylene compounds

Background: Recently, pyrimidine and chromene derivatives have concerned increasing attention because of the wide range of biological activities. Considering the prominence of pyrimidine and chromene derivatives, several procedures have been reported for the synthesis of these compounds. Herein, new magnetic nanoparticles supported ionic liquid has been evaluated for the synthesis of pyrimidine and chromene derivatives. Methods: In this method, pyrimidine and chromene compounds were synthesized by the multi-component reaction of aromatic aldehydes, malononitrile, and active methylene compounds in the presence of the new magnetic nanoparticles supported ionic liquid. The new nanocatalyst was characterized by using TEM, VSM, XRD and IR spectrum. Results: The remarkable advantages of this new procedure involve high yields, short experimental time, low cast and easy preparation of the catalyst and no need of any workup and purification. Magnetic properties of the catalyst led to the easy separation from the reaction mixture by using an external magnet. The catalyst can be reused several times in the desired reaction without significant decrease of its activity. Conclusion: An efficient and green method for the synthesis of chromene and pyrimidine compounds in the presence of magnetic nanoparticles supported ionic liquid have been developed. Thermal stability, low cost and easy synthesis of the catalyst, high yields, easy separation and purification of the product, short experimental time and using a green solvent such as water provided a useful and alternative method for such reactions.

Nanoammonium salt: a novel and recyclable organocatalyst for one-pot three-component synthesis of 2-amino-3-cyano-4H-pyran derivatives

1,3-Propanediaminium methanesulfonate [(PDA)(MeSO3)] was synthesized as the first nanoaliphatic ammonium salt via a safe and simple chemical route in aqueous media. [(PDA)(MeSO3)] ammonium salt was characterized by XRD, TEM, SEM, EDS

Synthesis, characterization and application of ZnFe2O4 nanoparticles as a heterogeneous ditopic catalyst for the synthesis of pyrano[2,3-d] pyrimidines

In the present work, ZnFe2O4 nanopowder, as a highly efficient and heterogeneous catalyst, was prepared and fully characterized by IR, UV, XRD, EDX and SEM analysis. The nanocatalyst was employed as a highly stable and reusable catal

Water Mediated Domino Knoevenagel-Michael-cyclocondensation Reaction of Malononitrile, Various Aldehydes and Barbituric Acid Derivatives Using Boric Acid Aqueous Solution System Compared with Nano-titania Sulfuric Acid

Nano-titania sulfuric acid (TSA) and boric acid [B(OH)3] were efficiently utilized for domino Knoevenagel-Michael-cyclocondensation reaction of malononitrile, various aldehydes and barbituric acid derivatives to synthesis of pyrano[2,3-d]pyrimi

Nickel nanoparticles as semiheterogeneous catalyst for one-pot, three-component synthesis of 2-amino-4H-pyrans and pyran annulated heterocyclic moieties

An efficient route for the synthesis of 2-amino-4H-pyrans and pyran annulated heterocyclic moieties has been reported via one-pot tandem Knoevenagel-cyclocondensation of aldehydes, malononitrile, and carbocyclic/heterocyclic 1,3-diones in the presence of