38024-35-0

Basic information

• Product Name: 3-Cinnolinecarboxamide, 4-amino-
• CAS NO: 38024-35-0
• Molecular Formula: C9H8N4O
• Molecular Weight: 188.189
• Mol File: 38024-35-0.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 3-Cinnolinecarboxamide, 4-amino-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Cinnolinecarboxamide, 4-amino-(38024-35-0)
• EPA Substance Registry System: 3-Cinnolinecarboxamide, 4-amino-(38024-35-0)

Safety Data

• Hazardous Substances Data: 38024-35-0(Hazardous Substances Data)

Upstream product

• 62-53-3 aniline 
• 20923-20-0 α-carboxamido-α-phenylhydrazonoacetonitrile 

Downstream Products

• 874903-56-7 2-(4-chlorophenyl)-pyrimido[5,4-c]cinnolin-4-ol 
• 874903-54-5 2-(4-methoxyphenyl)-pyrimido[5,4-c]cinnolin-4-ol 
• 874903-61-4 4-chloro-2-(2-methoxyphenyl)-pyrimido[5,4-c]cinnoline 
• 874903-60-3 4-chloro-2-(4-methoxyphenyl)-pyrimido[5,4-c]cinnoline 
• 874903-62-5 4-chloro-2-(4-chlorophenyl)-pyrimido[5,4-c]cinnoline 
• 874903-59-0 4-chloro-2-phenyl-pyrimido[5,4-c]cinnoline 
• 874903-53-4 2-phenyl-pyrimido[5,4-c]cinnolin-4(3H)-one 
• 143232-59-1 4-amino-3-cinnolinecarboxylic acid 
• 874903-55-6 2-(2-methoxyphenyl)-pyrimido[5,4-c]cinnolin-4-ol 

Relevant articles and documents

HETEROCYCLIC COMPOUNDS

The present invention relates to compounds of the general formula (1) wherein the variables are defined as given in the description and claims. The invention further relates to uses of and to, processes and intermediates related to compounds of the general formula (I), wherein Q is wherein the substituents of I, Ia and Ib are as defined in description and claims.

Synthesis, structures and biological activity of some 4-amino-3-cinnolinecarboxylic acid derivatives, part 1

This work describes the synthesis of 4-amino-3-cinnolinecarboxamides, which were then hydrolyzed to corresponding 4-amino-3-cinnolinecarboxylic acids. Several compounds were tested for their antibacterial and antifungal activity, and for the central nervous system effect.

Synthesis of 4-Aminocinnolines from (Arylhydrazono)(cyano)acetic Acid Derivatives

The intramolecular Friedel-Crafts reaction of (arylhydrazono)(cyano)acetamides and -malononitriles 1 yields the 4-amino-3-cinnolinecarboxylic acid derivatives 2.Toluene as solvent takes part in the reaction of 1d and e and forms the 4-amino-3-cinnolyl p-t