38029-16-2

Basic information

• Product Name: 3-HYDROXY-2,6-DI(HYDROXYMETHYL)PYRRIDINE HYDROCHLORIDE
• Synonyms: 3-HYDROXY-2,6-DIHYDROXYMETHYLPYRIDINE;3-HYDROXY-2,6-DI(HYDROXYMETHYL)PYRRIDINE HYDROCHLORIDE;3-HYDROXY-2,6-PYRIDINEDIMETHANOL HYDROCHLORIDE;2,6-BIS-HYDROXYMETHYL-PYRIDIN-3-OL;3-hydroxypyridine-2,6-dimethanol;3-HYDROXY-2,6-DI(HYDROXYMETHYL)PYRIDINE HYDROCHLORIDE;2,6-Bis(hydroxymethyl)-3-hydroxypyridine;2,6-Bis(hydroxymethyl)pyridine-3-ol
• CAS NO: 38029-16-2
• Molecular Formula: C₇H₉NO₃
• Molecular Weight: 191.61
• EINECS: 253-752-9
• Mol File: 38029-16-2.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 477.5°Cat760mmHg
• Flash Point: 242.6°C
• Appearance: /
• Density: 1.427g/cm³
• Vapor Pressure: 6.31E-10mmHg at 25°C
• Refractive Index: 1.639
• CAS DataBase Reference: 3-HYDROXY-2,6-DI(HYDROXYMETHYL)PYRRIDINE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-HYDROXY-2,6-DI(HYDROXYMETHYL)PYRRIDINE HYDROCHLORIDE(38029-16-2)
• EPA Substance Registry System: 3-HYDROXY-2,6-DI(HYDROXYMETHYL)PYRRIDINE HYDROCHLORIDE(38029-16-2)

Safety Data

• Hazardous Substances Data: 38029-16-2(Hazardous Substances Data)

Usage

General Description

3-Hydroxy-2,6-di(hydroxymethyl)pyridine hydrochloride is a chemical compound with potential medicinal applications. It is an intermediate in the synthesis of pharmaceuticals and can be used as a raw material for the production of pyridoxine hydrochloride, also known as Vitamin B6. 3-HYDROXY-2,6-DI(HYDROXYMETHYL)PYRRIDINE HYDROCHLORIDE is also used in the production of various drugs such as anti-tuberculosis drugs, antihistamines, and sedatives. Additionally, it is used for making food and feed additives, and as a dye intermediate. The hydrochloride salt form of this compound is water-soluble and can be easily handled and stored, making it suitable for various industrial applications.

InChI:InChI=1/C7H9NO3/c9-3-5-1-2-7(11)6(4-10)8-5/h1-2,9-11H,3-4H2

Upstream product

• 1204311-38-5 C₄₄H₄₀N₈O₁₇ 
• 109-00-2 3-HYDROXYPYRIDINE 
• 58958-50-2 methanol+acetone 
• 14187-25-8 3-hydroxy-2,6-bis(hydroxymethyl)pyridine hydrochloride 
• 50-00-0 formaldehyd 

Downstream Products

• 113231-32-6 3-hydroxy-2,6-pyridinedicarboxaldehyde 
• 910449-80-8 (12-benzyloxy-6,9-bis(methoxycarbonylmethyl)-3,6,9,15-tetraazabicyclo[9.3.1]-pentadeca-1⁽¹⁴⁾,11⁽¹⁵⁾,12-trien-3-yl)acetic acid, methyl ester of 
• 910449-77-3 3-benzyloxy-2,6-bis(bromomethyl)pyridine 
• 910449-81-9 (12-Benzyloxy-6,9-bis(carboxymethyl)-3,6,9,15-tetraazabicyclo[9.3.1]-pentadeca-1⁽¹⁴⁾,11⁽¹⁵⁾,12-trien-3-yl)acetic acid 
• 910449-79-5 12-benzyloxy-3,6,9,15-tetraazabicyclo[9.3.1]pentadeca-1⁽¹⁵⁾,11,13-triene 
• 910449-78-4 12-benzyloxy-3,6,9-tris(2-nitrobenzenesulfonyl)-3,6,9,15-tetraazabicyclo[9.3.1]pentadeca-1⁽¹⁵⁾,11,13-triene 
• 755692-12-7 3-benzyloxy-2,6-bis(hydroxymethyl)pyridine 
• 38199-60-9 12-(2-phenyl-4H-[1,3]dioxino[5,4-b]pyridin-6-yl)-dodecan-2-ol 
• 38199-55-2 triphenyl-(2-phenyl-4H-[1,3]dioxino[5,4-b]pyridin-6-ylmethyl)-phosphonium; chloride 
• 38324-61-7 2-phenyl-6-(11-tetrahydropyran-2-yloxy-dodec-1-enyl)-4H-[1,3]dioxino[5,4-b]pyridine 
• 38199-54-1 6-chloromethyl-2-phenyl-4H-[1,3]dioxino[5,4-b]pyridine 
• 227457-56-9 3-(4-Bromobenzyloxy)-2,6-bis(hydroxymethyl)pyridine 
• 14187-25-8 3-hydroxy-2,6-bis(hydroxymethyl)pyridine hydrochloride 
• 38199-16-5 (2-phenyl-4H-[1,3]dioxino[5,4-b]pyridin-6-yl)-methanol 

Relevant articles and documents

Synthesis and biological activity of quaternary phosphonium salts based on 3-hydroxypyridine and 4-deoxypyridoxine

Methods for the synthesis of quaternary phosphonium salts based on 3-hydroxypyridine and 4-deoxypyridoxine were developed. Some of obtained compounds possess high antibacterial and antitumor activity in vitro.

Lipophilic chelates and their use in imaging

The invention relates to chelate compounds which can be used in MRI, the chelates being intended to be conveyed by lipophilic transporters, such as lipid nanoparticles or liposomes. The invention also relates to compounds comprising, in association, these chelates and these transporters, if appropriate connected via chemical bonding groups, and to their use in diagnostic imaging, it being possible for this association additionally to comprise biological targeting markers, denoted biovectors.

Synthesis of a novel amphiphilic GdPCTA-[12] derivative as a potential micellar MRI contrast agent

A novel amphiphilic contrast agent, a GdPCTA-[12] derivative containing a dodecyl chain as lipophilic moiety, has been prepared. A convergent synthetic route from commercially available diethylene triamine and 3-hydroxypyridine is described. The target amphiphilic gadolinium complex was obtained in nine steps in 22% overall yield. Physicochemical properties and relaxivity measurements of this new contrast agent are described.