380467-91-4

Usage

Molecular Structure

The compound has a complex molecular structure with a benzo[b]thiophene ring as its base.

Functional Groups

It contains a carboxylic acid, an ethyl ester, and a cyano-acetylamino group as its functional groups.

Derivative

The cyano-acetylamino group is a derivative of acetyl and amino groups.

Potential Applications

The compound may have potential applications in various fields such as pharmaceuticals, agrochemicals, or materials science due to its unique structure and functional groups.

Further Research

More research and testing are needed to fully understand its potential uses and properties.

Upstream product

• 4506-71-2 ethyl 2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate 
• 36140-83-7 1-cyanoacetyl-3,5-dimethylpyrazole 

Relevant academic research and scientific papers

Computational studies and sever apoptotic bioactivity of new heterocyclic cyanoacrylamide based p-fluorophenyl and p-phenolic compounds against liver carcinoma (Hepg2)

An efficient route for the preparation of new heterocyclic cyanoacrylamides based p-fluorophenyl and p-phenolic compounds was depicted. All structures were confirmed based on the different spectral tools and elemental analyses. MTT assay for the novel syn

Synthesis, characterization, antioxidant and antitumor evaluation of some new thiazolidine and thiazolidinone derivatives

2-(2-Cyano-acetylamino)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid ethyl ester (2) was utilized as a key intermediate for the synthesis of thiocarbamoyl derivative 3 via its reaction with phenyl isothiocyanate. Treatment of 3 with chloroacetyl chloride afforded thiazolidin-5-one 4. Compound 7 reacted with different α-halo carbonyl compounds to give thiazolidine 8a,b, and thiazolidin-4-one derivatives 9. Treatment of 4 with the appropriate aromatic aldehyde and tolyl diazonium chloride afforded the corresponding thiazolidin-5-one derivatives 5a,b and 6, respectively. The thiazolidin-4-one derivative 10 was obtained via the reaction of compound 2 with 2-mercaptoacetic acid. Finally, the thiazoline 11 was obtained via the reaction of compound 2 with phenyl isothiocyanate/sulfur. The title compounds were characterized by elemental analyses and spectral data. The quantum mechanical calculations for some compounds were accomplished and subjected for antioxidant and antitumor studies, whereas, some of them exhibited promising activities.

Cyanoacetamide in heterocyclic chemistry: Synthesis, antitumor and antioxidant activities of some new benzothiophenes

Cyanoacylation of 2-amino-tetrahydrobenzothiophene-3-carboxylate ethyl ester with 3-(3,5-dimethyl-1H-pyrazol-1-yl)-3-oxopropanenitrile afforded cyanoacetamide 2. The later was utilized as key intermediate for the synthesis of 3-substituted 2-iminocoumarin