380634-52-6

Basic information

• Product Name: 6-tert-butyl-4-hydroxy-1-phenyl-2(1H)-pyridinone
• Synonyms: 6-tert-butyl-4-hydroxy-1-phenyl-2(1H)-pyridinone
• CAS NO: 380634-52-6
• Molecular Formula: C15H17NO2
• Molecular Weight: 243.30098
• Mol File: 380634-52-6.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 6-tert-butyl-4-hydroxy-1-phenyl-2(1H)-pyridinone(CAS DataBase Reference)
• NIST Chemistry Reference: 6-tert-butyl-4-hydroxy-1-phenyl-2(1H)-pyridinone(380634-52-6)
• EPA Substance Registry System: 6-tert-butyl-4-hydroxy-1-phenyl-2(1H)-pyridinone(380634-52-6)

Safety Data

• Hazardous Substances Data: 380634-52-6(Hazardous Substances Data)

Upstream product

• 503426-27-5 6-tert-butyl-3-acetyl-4-hydroxy-1-phenylpyridin-2(1H)-one 

Relevant articles and documents

Synthesis of Acetyl and Iodo Derivatives of 4-Hydroxy-6-phenyl-6H-pyrano[3,2-c]pyridine-2,5-diones and 4-Hydroxy-1-phenylpyridin-2(1H)-ones

A simple and efficient method has been described for the synthesis of acetyl and iodo derivatives of 4-hydroxy-6-phenyl-6H-pyrano[3,2-c]pyridine-2,5-diones 1 and 4-hydroxy-1-phenylpyridin-2(1H)-ones 5. Compounds 1 with phenyl and alkyl substituent at C(7) and C(8), respectively, can be easily acetylated by refluxing in a mixture of acetic acid and polyphosphoric acid to give 3-acetyl-4-hydroxy-6-phenyl-6H-pyrano[3,2-c]pyridine-2,5-diones 2 in excellent yields. Compounds 1 and 5 can be iodinated with iodine and anhydrous sodium carbonate in boiling dioxane to give 4-hydroxy-3-iodo-6-phenyl-6H-pyrano[3,2-c]pyridine-2,5-diones 3 and 4-hydroxy-3-iodo-1-phenylpyridin-2(1H)-ones 6, respectively, in good yields. The structures were confirmed using infrared, nuclear magnetic resonance, and elemental analysis.