380635-56-3

Upstream product

• 380635-49-4 4,8-bis(benzyloxycarbonyl)-N¹-[N^α,N^ε-bis(benzyloxycarbonyl)-L-lysyl]-N¹²-t-butoxycarbonyl-4,8-diaza-1,12-dodecanediamine 
• 380635-51-8 4,8-bis(benzyloxycarbonyl)-N¹-[N^α,N^ε-bis(benzyloxycarbonyl)-L-lysyl]-4,8-diaza-1,12-dodecanediamine 
• 380635-54-1 4,8-bis(benzyloxycarbonyl)-N¹-[N^α,N^ε-bis(benzyloxycarbonyl)-L-lysyl]-N¹²-[N^α-(t-butoxycarbonyl)-L-asparaginyl]-4,8-diaza-1,12-dodecanediamine 

Downstream Products

• 380635-59-6 4,8-bis(benzyloxycarbonyl)-N¹-[N^α,N^ε-bis(benzyloxycarbonyl)-L-lysyl]-N¹²-{N^α-[2,4-bis(benzyloxy)phenylacetyl]-L-asparaginyl}-4,8-diaza-1,12-dodecanediamine 

Relevant academic research and scientific papers

Total synthesis of the novel spider toxin NPTX-594 from Nephila madagascariencis

A novel spider toxin, NPTX-594, comprised of four constituents: i.e., 2,4-dihydroxyphenylacetic acid (Dhpa), asparagine, 4,8-diaza-1,12-dodecanediamine (Dada), and lysine, was chemically synthesized. The synthetic compound was completely identical with the natural product as regards 1H NMR and mass spectra. The structure of NPTX-594 was thus determined synthetically to be N12-(Dhpa-Asn)-N1-Lys-Dada, as proposed by spectrometric elucidation.