38071-61-3Relevant academic research and scientific papers
Visible-light-induced formation of thiavinyl 1,3-dipoles: A metal-free [3+2] oxidative cyclization with alkynes as easy access to thiophenes
Zheng, Baihui,Li, Xiaotong,Song, Yang,Meng, Shuyang,Li, Yifei,Liu, Qun,Pan, Ling
, p. 3453 - 3459 (2021)
A visible-light-induced [3+2] oxidative cyclization of various alkynes with easily available ketene dithioacetals as the previously unknown thiavinyl 1,3-dipoles in the presence of an acridine photosensitizer is reported. A series of multisubstituted thiophenes were achieved regioselectively in ≤98% yields under very mild metal-free conditions without other additives. This reaction could tolerate a wide range of substrates and achieve good efficiency in large-scale syntheses. The reaction mechanism and their applications are described in detail to reveal the reactivity of the new 1,3-dipoles and the selectivity of the reactions.
COMPOUNDS FOR THE TREATMENT OF PARAMOXYVIRUS VIRAL INFECTIONS
-
Paragraph 0547, (2014/03/25)
Disclosed herein are new antiviral compounds, together with pharmaceutical compositions that include one or more antiviral compounds, and methods of synthesizing the same. Also disclosed herein are methods of ameliorating and/or treating a paramyxovirus viral infection with one or more small molecule compounds. Examples of paramyxovirus infection include an infection caused by human respiratory syncytial virus (RSV).
Polychromic tetracyclo-spiro-adamatylidene derivatives, and polychromic lens incorporating said compounds
-
, (2008/06/13)
A series of photochromic compounds are disclosed which have the property of undergoing a reversible color change when exposed to unfiltered sunlight and reverting to their original color in the absence of U.V. light at room temperature. These compounds have the general formula: STR1 represents an adamantylidene or a substituted adamantylidene group; R1 represents hydrogen, alkyl, aryl, aralkyl or a heterocyclic group, X represents oxygen or > NR2, in which R2 is hydrogen, aryl, alkyl or aralkyl and STR2 represents an aromatic group, an unsaturated heterocyclic group or a benzannelated heterocyclic group. The photochromic compounds of the invention are useful in the manufacture of photoreactive lenses, particularly plastic lenses.
